Bruneval P, Guermonprez J L, Perrier P, Carpentier A, Camilleri J P
Arch Pathol Lab Med. 1986 Dec;110(12):1186-7.
Morphological changes are described in a case of coronary restenosis occurring three and ten months after transluminal coronary angioplasty. The lesions consisted of severe narrowing of the previously mechanically dilated coronary segments. This narrowing was produced by fibrocellular intimal hyperplasia associated with rupture of the media whereas the atheromatous plaque was not involved. This suggests that medial injury associated with healing intimal hyperplasia could be the major factor resulting in late coronary restenosis.
本文描述了1例经皮腔内冠状动脉成形术后3个月和10个月发生冠状动脉再狭窄的形态学变化。病变表现为先前机械扩张的冠状动脉节段严重狭窄。这种狭窄是由与中膜破裂相关的纤维细胞内膜增生引起的，而动脉粥样斑块未受累。这表明与愈合性内膜增生相关的中膜损伤可能是导致晚期冠状动脉再狭窄的主要因素。
