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Molecular basis for histidine N1 position-specific methylation by CARNMT1.

作者信息

Cao Ruili, Zhang Xingrun, Liu Xiaohui, Li Yuanyuan, Li Haitao

机构信息

MOE Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, 100084, China.

Lipidomics and Metabolomics Centre, National Protein Science Facility, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

出版信息

Cell Res. 2018 Apr;28(4):494-496. doi: 10.1038/s41422-018-0003-0. Epub 2018 Feb 20.

DOI:10.1038/s41422-018-0003-0
PMID:29463897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5938892/
Abstract
摘要

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本文引用的文献

1
Substrate Recognition Mechanism of the Putative Yeast Carnosine N-methyltransferase.假定的酵母肌肽N-甲基转移酶的底物识别机制
ACS Chem Biol. 2017 Aug 18;12(8):2164-2171. doi: 10.1021/acschembio.7b00328. Epub 2017 Jul 13.
2
Methylation of yeast ribosomal protein Rpl3 promotes translational elongation fidelity.酵母核糖体蛋白Rpl3的甲基化促进翻译延伸保真度。
RNA. 2016 Apr;22(4):489-98. doi: 10.1261/rna.054569.115. Epub 2016 Jan 29.
3
UPF0586 Protein C9orf41 Homolog Is Anserine-producing Methyltransferase.UPF0586蛋白C9orf41同源物是肌肽生成甲基转移酶。
J Biol Chem. 2015 Jul 10;290(28):17190-205. doi: 10.1074/jbc.M115.640037. Epub 2015 May 22.
4
Histidine methylation of yeast ribosomal protein Rpl3p is required for proper 60S subunit assembly.酵母核糖体蛋白Rpl3p的组氨酸甲基化是60S亚基正确组装所必需的。
Mol Cell Biol. 2014 Aug;34(15):2903-16. doi: 10.1128/MCB.01634-13. Epub 2014 May 27.
5
The multiple roles of histidine in protein interactions.组氨酸在蛋白质相互作用中的多种作用。
Chem Cent J. 2013 Mar 1;7(1):44. doi: 10.1186/1752-153X-7-44.
6
A novel 3-methylhistidine modification of yeast ribosomal protein Rpl3 is dependent upon the YIL110W methyltransferase.酵母核糖体蛋白 Rpl3 的一种新型 3-甲基组氨酸修饰依赖于 YIL110W 甲基转移酶。
J Biol Chem. 2010 Nov 26;285(48):37598-606. doi: 10.1074/jbc.M110.170787. Epub 2010 Sep 23.
7
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers.染色质结合模块如何解读组蛋白修饰:来自专业扒手的启示。
Nat Struct Mol Biol. 2007 Nov;14(11):1025-1040. doi: 10.1038/nsmb1338. Epub 2007 Nov 5.
8
Mechanism of histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity.蛋白质赖氨酸甲基转移酶SET7/9催化组蛋白甲基化的机制及产物特异性的起源
Proc Natl Acad Sci U S A. 2007 May 22;104(21):8797-802. doi: 10.1073/pnas.0702981104. Epub 2007 May 15.
9
Amino acid sequence aroung 3-methylhistidine in rabbit skeletal muscle actin.兔骨骼肌肌动蛋白中3-甲基组氨酸周围的氨基酸序列。
Biochemistry. 1971 Jan 19;10(2):224-9. doi: 10.1021/bi00778a005.