FOCUS试验后的输血率趋势。
Trends in transfusion rates after the FOCUS trial.
作者信息
Howard David H, Roback John D, Murphy David J
机构信息
Department of Health Policy & Management, Emory University, Atlanta, GA 303222, USA.
Department of Pathology & Laboratory Medicine, Center for Transfusion & Cellular Therapies, Emory University, Atlanta, GA 303223, USA.
出版信息
J Comp Eff Res. 2018 Feb;7(2):113-120. doi: 10.2217/cer-2017-0038. Epub 2018 Feb 21.
AIM
We estimate the impact of the FOCUS trial, which concluded that hip surgery patients with hemoglobin values above 8 g/dl do not benefit from routine transfusions, on transfusion rates.
METHODS
We evaluated trends in transfusion rates using inpatient discharge data from four states.
RESULTS
The transfusion rate was 5.2 percentage points lower in the fourth quarter of 2013 than it would have been had pre-FOCUS trends continued. Transfusion rates declined more in hospitals with a low end-of-life treatment intensity index, a general measure of treatment intensity.
CONCLUSION
The FOCUS trial affected practice, but there are additional opportunities to reduce the use of transfusions.
目的
我们评估了FOCUS试验对输血率的影响，该试验得出结论，血红蛋白值高于8g/dl的髋关节手术患者无法从常规输血中获益。
方法
我们使用来自四个州的住院患者出院数据评估输血率趋势。
结果
2013年第四季度的输血率比FOCUS试验前趋势持续时低5.2个百分点。在临终治疗强度指数较低（一种治疗强度的总体衡量指标）的医院中，输血率下降幅度更大。
结论
FOCUS试验影响了医疗实践，但仍有进一步降低输血使用率的机会。
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