Sitaula Sanjeeta, Dahal Hira Nath, Sharma Ananda Kumar
B. P. Koirala Lions Centre for Ophthalmic Studies, Institute of Medicine, Maharajgunj, Kathmandu, Nepal.
Neuroophthalmology. 2017 Jun 21;42(1):17-24. doi: 10.1080/01658107.2017.1331362. eCollection 2018 Feb.
This study aims to report the clinical features and role of different treatment modalities in final visual outcome in traumatic optic neuropathy (TON). The authors retrospectively reviewed the records of patients with TON over 4 years. There were 37 patients of unilateral TON. Mean age was 28.70 ± 15.20 years (range: 8-90) and 89% ( = 33) were males. Road traffic accident was the common cause (43.2%), followed by fall injury (35.1%). There was improvement of visual acuity in 51.4% ( = 19) cases. Out of different treatment modalities, high-dose intravenous methylprednisolone (1 g/day) led to significant improvement in final visual acuity ( = 0.013). There was no significant improvement in final visual outcome in patients with poor initial visual acuity and those with intracranial injuries.
本研究旨在报告创伤性视神经病变（TON）的临床特征以及不同治疗方式对最终视力结果的作用。作者回顾性分析了4年间TON患者的病历记录。共有37例单侧TON患者。平均年龄为28.70±15.20岁（范围：8 - 90岁），89%（n = 33）为男性。道路交通事故是常见原因（43.2%），其次是跌倒损伤（35.1%）。51.4%（n = 19）的病例视力有所改善。在不同的治疗方式中，大剂量静脉注射甲基强的松龙（1 g/天）使最终视力有显著改善（P = 0.013）。初始视力差的患者和有颅内损伤的患者在最终视力结果上没有显著改善。
