Gui-Sheng Ding, Chun-Rong Xiong, Cai-Qun Cao, De-Rong Hang, Ping Miao, Ya-Fei Chen, Bo-Chao Sun, Yi-Xin Huang
Nantong Municipal Center for Disease Control and Prevention, Jiangsu Province, Nantong 226007, China.
Key Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Jiangsu Province, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2017 Dec 18;29(6):784-787. doi: 10.16250/j.32.1374.2017150.
To understand the forming cause of the snail-existent non-endemic areas of schistosomiasis (SENEAS), and to verify the conclusion of previous studies, so as to provide the evidence for schistosomiasis monitoring in such areas in Nantong City, Jiangsu Province.
The controlled field tests were carried out to observe the snails artificially infected by schistosome miracidia in SENEAS. The influence of the soil from SENEAS and the endemic areas on snails artificially infected by miracidia were observed.
All the experimental snails could be infected by schistosome miracidia except the smooth-shell snails from Tangyuan Village in the controlled field test environment of SENEAS or the endemic areas. The infection rates of the smooth-shell snails were lower than those of the ribbed-shell snails, but there were no statistically significant differences. The mortality rates of the smooth-shell snails were higher than those of the ribbed - shell snails, which were statistically significant ( = 135.118, = 122.836, =154.436, = 138.288, = 151.923, all < 0.01). There were no significant differences in the infection rates of snails between each test group of the soil from SENEAS and the endemic areas ( = 0.071, = 0.216, both > 0.05). Also there was no significant difference between each test group and the control group without soil ( = 7.148, > 0.05).
It is likely to form the spread of schistosomiasis in SENEAS in Nantong City with sufficient amount of infection source of schistosomiasis imported. It is still necessary to implement the surveillance of schistosomiasis and snails in Nantong City.
了解江苏省南通市血吸虫病流行村（SENEAS）的形成原因，验证既往研究结论，为南通市此类地区的血吸虫病监测提供依据。
进行对照现场试验，观察SENEAS和流行区经血吸虫毛蚴人工感染的钉螺。观察SENEAS和流行区土壤对经毛蚴人工感染钉螺的影响。
在SENEAS或流行区的对照现场试验环境中，除塘园村的光壳钉螺外，所有试验钉螺均可被血吸虫毛蚴感染。光壳钉螺的感染率低于肋壳钉螺，但差异无统计学意义。光壳钉螺的死亡率高于肋壳钉螺，差异有统计学意义（χ² = 135.118，χ² = 122.836，χ² = 154.436，χ² = 138.288，χ² = 151.923，均P < 0.01）。SENEAS和流行区土壤各试验组钉螺感染率差异无统计学意义（χ² = 0.071，χ² = 0.216，均P > 0.05）。各试验组与无土壤对照组差异也无统计学意义（χ² = 7.148，P > 0.05）。
南通市SENEAS地区在有足够血吸虫病传染源输入的情况下，有可能形成血吸虫病传播。南通市仍有必要开展血吸虫病和钉螺监测。
