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Local skin reactions following the administration of topical ingenol mebutate for actinic keratosis.

作者信息

Conde-Taboada Alberto, Mercado Bárbara, Aranegui Beatriz, González-Guerra Elena, López-Bran Eduardo

机构信息

Dermatology Department, Hospital Clínico San Carlos, Madrid, Spain.

出版信息

Dermatol Online J. 2017 Sep 15;23(9):13030/qt610558x9.

PMID:29469731
Abstract

Actinic keratoses are cutaneous lesions that appear as the result of the proliferation of atypical keratinocytes. These lesions are considered pre-malignant and they can progress to squamous cell carcinoma. Ingenol mebutate has been approved as an effective treatment for AK on the face and trunk. We studied the local skin reactions to this therapy. Data about local skin reactions were collected in a series of 5 patients with photographic documentation, a visual analog scale, and a ranking of satisfaction of the patient. Moderate to severe reactions were reported in most of patients, but only one stopped treatment early. The short duration of treatment contributes to high adherence to the therapy.

摘要

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