Croft Janet B, Wheaton Anne G, Liu Yong, Xu Fang, Lu Hua, Matthews Kevin A, Cunningham Timothy J, Wang Yan, Holt James B
Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, CDC.
MMWR Morb Mortal Wkly Rep. 2018 Feb 23;67(7):205-211. doi: 10.15585/mmwr.mm6707a1.
Chronic obstructive pulmonary disease (COPD) accounts for the majority of deaths from chronic lower respiratory diseases, the third leading cause of death in the United States in 2015 and the fourth leading cause in 2016.* Major risk factors include tobacco exposure, occupational and environmental exposures, respiratory infections, and genetics. State variations in COPD outcomes (1) suggest that it might be more common in states with large rural areas. To assess urban-rural variations in COPD prevalence, hospitalizations, and mortality; obtain county-level estimates; and update state-level variations in COPD measures, CDC analyzed 2015 data from the Behavioral Risk Factor Surveillance System (BRFSS), Medicare hospital records, and death certificate data from the National Vital Statistics System (NVSS). Overall, 15.5 million adults aged ≥18 years (5.9% age-adjusted prevalence) reported ever receiving a diagnosis of COPD; there were approximately 335,000 Medicare hospitalizations (11.5 per 1,000 Medicare enrollees aged ≥65 years) and 150,350 deaths in which COPD was listed as the underlying cause for persons of all ages (40.3 per 100,000 population). COPD prevalence, Medicare hospitalizations, and deaths were significantly higher among persons living in rural areas than among those living in micropolitan or metropolitan areas. Among seven states in the highest quartile for all three measures, Arkansas, Kentucky, Mississippi, and West Virginia were also in the upper quartile (≥18%) for rural residents. Overcoming barriers to prevention, early diagnosis, treatment, and management of COPD with primary care provider education, Internet access, physical activity and self-management programs, and improved access to pulmonary rehabilitation and oxygen therapy are needed to improve quality of life and reduce COPD mortality.
慢性阻塞性肺疾病(COPD)是慢性下呼吸道疾病导致死亡的主要原因,在2015年是美国第三大死因,2016年是第四大死因。*主要风险因素包括接触烟草、职业和环境暴露、呼吸道感染以及遗传因素。COPD相关结果的州际差异(1)表明,在农村面积较大的州,COPD可能更为常见。为评估COPD患病率、住院率和死亡率的城乡差异;获取县级估计数据;并更新COPD相关指标的州级差异,美国疾病控制与预防中心(CDC)分析了2015年行为危险因素监测系统(BRFSS)、医疗保险医院记录以及国家生命统计系统(NVSS)的死亡证明数据。总体而言,1550万年龄≥18岁的成年人(年龄调整患病率为5.9%)报告曾被诊断患有COPD;约有33.5万例医疗保险住院病例(每1000名年龄≥65岁的医疗保险参保者中有11.5例),所有年龄段中有150350例死亡病例将COPD列为根本死因(每10万人中有40.3例)。农村地区居民的COPD患病率、医疗保险住院率和死亡率显著高于微型都市或大都市地区居民。在所有三项指标处于最高四分位数的七个州中,阿肯色州、肯塔基州、密西西比州和西弗吉尼亚州农村居民的该项指标也处于上四分位数(≥18%)。需要通过对初级保健提供者进行教育、提供互联网接入、开展体育活动和自我管理项目以及改善肺部康复和氧疗的可及性,来克服COPD预防、早期诊断、治疗和管理方面的障碍,以提高生活质量并降低COPD死亡率。