Although the precise pathophysiology of pre-eclampsia remains unknown, this condition continues to be a major cause of maternal and fetal mortality and morbidity. Early prediction of pre-eclampsia would allow for timely initiation of preventive therapy A combination of biophysical and biochemical markers are superior to other tests for early prediction of the development of pre-eclampsia. This article reviews the current research of the most important strategies for prediction of pre-eclampsia, including the use of maternal risk factors, mean maternal arterial pressure, ultrasound parameters, and biomarkers.
虽然子痫前期的确切病理生理学仍不清楚，但这种情况仍然是孕产妇和胎儿死亡及发病的主要原因。子痫前期的早期预测将有助于及时启动预防性治疗。生物物理和生化标志物的组合在子痫前期发展的早期预测方面优于其他检测方法。本文综述了目前关于子痫前期预测最重要策略的研究，包括使用孕产妇风险因素、平均孕产妇动脉压、超声参数和生物标志物。
