Department of Biomedical Data Sciences, Stanford University, Stanford, California.
Department of Biomedical Engineering, Stanford University, Stanford, California.
Wiley Interdiscip Rev Syst Biol Med. 2018 Jul;10(4):e1417. doi: 10.1002/wsbm.1417. Epub 2018 Feb 23.
As precision medicine becomes increasingly relevant in healthcare, the field of pharmacogenomics (PGx) also continues to gain prominence in the clinical setting. Leading institutions have begun to implement PGx testing and the amount of published PGx literature increases yearly. The Pharmacogenomics Knowledgebase (PharmGKB; www.pharmgkb.org) is one of the foremost worldwide resources for PGx knowledge, and the organization has been adapting and refocusing its mission along with the current revolution in genomic medicine. The PharmGKB website provides a diverse array of PGx information, from annotations of the primary literature to guidelines for adjusting drug treatment based on genetic information. It is freely available and accessible to everyone from researchers to clinicians to everyday citizens. PharmGKB was found over 17 years ago, but continues to be a vital resource for the entire PGx community and the general public. This article is categorized under: Translational, Genomic, and Systems Medicine > Translational Medicine.
随着精准医学在医疗保健领域的相关性日益增强,药物基因组学(PGx)领域在临床环境中也继续受到关注。领先的机构已经开始实施 PGx 测试,并且每年发表的 PGx 文献数量也在增加。药物基因组学知识库(PharmGKB;www.pharmgkb.org)是全球最重要的 PGx 知识资源之一,该组织一直在随着基因组医学的当前革命进行调整和重新定位其使命。PharmGKB 网站提供了各种 PGx 信息,从对原始文献的注释到根据遗传信息调整药物治疗的指南。它是免费的,可供研究人员、临床医生和普通市民等所有人使用。PharmGKB 成立于 17 年多前,但它仍然是整个 PGx 社区和普通大众的重要资源。本文归类于:转化、基因组和系统医学 > 转化医学。