From the Pediatric Infectious Disease Unit, Robert-Debré University Hospital, Assistance Publique Hôpitaux de Paris.
Immunobiology Unit, Georges Pompidou University Hospital, Assistance Publique Hôpitaux de Paris.
Pediatr Infect Dis J. 2018 Oct;37(10):1014-1015. doi: 10.1097/INF.0000000000001966.
We report an unusual case of generalized necrotic purpuric rash that started 48 hours after the initiation of effective third-generation cephalosporin therapy to treat Neisseria meningitidis W infection in a 12-year-old girl. The course was favorable with no shock, and she recovered completely without sequelae. This infection revealed C6 deficiency in our patient.
我们报告了一例不常见的全身性坏死性紫癜皮疹病例,该病例发生于 12 岁女孩开始使用第三代头孢菌素有效治疗脑膜炎奈瑟菌 W 感染后 48 小时。患者无休克,病情顺利,无后遗症完全康复。该感染揭示了我们患者存在 C6 缺乏。