EPIC-CoGe：管理和分析基因组数据。
EPIC-CoGe: managing and analyzing genomic data.
机构信息
BIO5 Institute, School of Plant Sciences, University of Arizona, Tucson, AZ, USA.
Department of Biology, University of Pennsylvania, Philadelphia, PA, USA.
出版信息
Bioinformatics. 2018 Aug 1;34(15):2651-2653. doi: 10.1093/bioinformatics/bty106.
SUMMARY
The EPIC-CoGe browser is a web-based genome visualization utility that integrates the GMOD JBrowse genome browser with the extensive CoGe genome database (currently containing over 30 000 genomes). In addition, the EPIC-CoGe browser boasts many additional features over basic JBrowse, including enhanced search capability and on-the-fly analyses for comparisons and analyses between all types of functional and diversity genomics data. There is no installation required and data (genome, annotation, functional genomic and diversity data) can be loaded by following a simple point and click wizard, or using a REST API, making the browser widely accessible and easy to use by researchers of all computational skill levels. In addition, EPIC-CoGe and data tracks are easily embedded in other websites and JBrowse instances.
AVAILABILITY AND IMPLEMENTATION
EPIC-CoGe Browser is freely available for use online through CoGe (https://genomevolution.org). Source code (MIT open source) is available: https://github.com/LyonsLab/coge.
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
摘要
EPIC-CoGe 浏览器是一个基于网络的基因组可视化工具，它将 GMOD JBrowse 基因组浏览器与广泛的 CoGe 基因组数据库（目前包含超过 30000 个基因组）集成在一起。此外，EPIC-CoGe 浏览器拥有许多基本 JBrowse 所没有的额外功能，包括增强的搜索功能，以及在所有类型的功能和多样性基因组数据之间进行即时分析和比较的功能。无需安装，只需按照简单的点击向导即可加载数据（基因组、注释、功能基因组和多样性数据），或者使用 REST API，使浏览器能够被所有计算技能水平的研究人员广泛访问和轻松使用。此外，EPIC-CoGe 和数据轨迹可以轻松嵌入其他网站和 JBrowse 实例中。
可用性和实现
EPIC-CoGe 浏览器可通过 CoGe（https://genomevolution.org）在线免费使用。源代码（MIT 开源）可在：https://github.com/LyonsLab/coge 上获取。
补充信息
补充数据可在 Bioinformatics 在线获取。
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