Ngaile J E, Msaki P K, Mvungi R, Schreiner L J
Department of Physics, University of Dar es Salaam, Dar es Salaam, Tanzania.
Jakaya Kikwete Cardiac Institute, Muhimbili National Hospital, Dar es Salaam, Tanzania.
Radiat Prot Dosimetry. 2018 Nov 1;181(4):317-332. doi: 10.1093/rpd/ncy030.
Although contemporary cardiac X-ray exams are typically set so benefits outweighs the risk, the growing use and increasing complexity of the cardiovascular interventional radiological (CVIR) procedures does increase the risk of radiation-related tissue effects and stochastic effects to the individual patients and the population. In view of these radiological concerns there is a need to investigate factors that influence the doses received by the patients and enable optimisation needed. The air kerma area product (KAP), cumulative air kerma (CAK) and fluoroscopy time (FT) to patients from two major CVIR procedures: coronary angiography (CA) and percutaneous coronary interventions (PCI), were obtained from two major hospitals in Tanzania. The CAK and KAP were determined using ionisation chambers equipped in each angiographic unit. The median values of the KAP, CAK and FT for the CA procedures were 37.8 Gy cm2, 425.5 mGy and 7.6 min, respectively, while for the PCI were 86.5 Gy cm2, 1180.3 mGy and 19.0 min, respectively. The overall differences among individual KAP, CAK and FT values across the two hospitals investigated differed by factors of up to 33.5, 58.7 and 26.3 for the CA, while for the PCI procedures differed by factors of up to 10.9, 25.3 and 13.8, respectively. The mean values of KAP and FT for both CA and PCI were mostly higher than those reported values for Ireland, Belgium, Greece, France, China and Australia. The third quartiles of the KAP, CAK and FT for both CA and PCI were relatively above the preliminary diagnostic reference levels proposed by the IAEA, DIMOND III and SENTINEL. The observed substantial variations of mean values of technical parameters and patient doses (KAP, CAK and FT values) observed for the CA and PCI procedures inter and intra-hospitals were mainly explained by the complexity of the CVIR procedures, the nature of pathology, patient-specific characteristics, the variation in levels of skills and experiences among IC personnel, and the different procedural protocols employed among interventional cardiologists and hospitals. The observed great variations of procedural protocols and patient doses within and across the hospitals and relative higher dose than reported values from the literature call for the need to optimise radiation dose to patient from IC procedures.
尽管当代心脏X射线检查通常设定为益处大于风险,但心血管介入放射学(CVIR)程序的使用不断增加且复杂性不断提高,确实增加了个体患者和人群遭受辐射相关组织效应和随机效应的风险。鉴于这些放射学问题,有必要调查影响患者所接受剂量的因素,并实现所需的优化。从坦桑尼亚的两家主要医院获取了两种主要CVIR程序(冠状动脉造影(CA)和经皮冠状动脉介入治疗(PCI))中患者的空气比释动能面积乘积(KAP)、累积空气比释动能(CAK)和透视时间(FT)。CAK和KAP使用每个血管造影设备中配备的电离室进行测定。CA程序的KAP、CAK和FT的中位数分别为37.8 Gy cm²、425.5 mGy和7.6分钟,而PCI程序的分别为86.5 Gy cm²、1180.3 mGy和19.0分钟。在所调查的两家医院中,CA的个体KAP、CAK和FT值的总体差异分别高达33.5、58.7和26.3倍,而PCI程序的差异分别高达10.9、25.3和13.8倍。CA和PCI的KAP和FT平均值大多高于爱尔兰、比利时、希腊、法国、中国和澳大利亚报告的数值。CA和PCI的KAP、CAK和FT的第三四分位数相对高于国际原子能机构、DIMOND III和SENTINEL提出的初步诊断参考水平。在医院内部和医院之间观察到的CA和PCI程序的技术参数平均值和患者剂量(KAP、CAK和FT值)的显著差异,主要是由CVIR程序的复杂性、病理性质、患者特定特征、介入放射科人员技能和经验水平的差异以及介入心脏病专家和医院采用的不同程序方案所导致的。在医院内部和医院之间观察到的程序方案和患者剂量的巨大差异以及相对于文献报告值的相对较高剂量,表明需要优化介入放射程序对患者的辐射剂量。