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白头翁根提取物对光滑念珠菌的抗真菌活性

ANTIFUNGAL ACTIVITY OF THE ROOT EXTRACTS OF PULSATILLA PATENS AGAINST CANDIDA GLABRATA.

作者信息

Laskai Grazyna, Sienkiewicz Aneta, Zjawiony Jordan K, Jacob Melissa, Khan Shabana

出版信息

Acta Pol Pharm. 2017 Jan;74(1):179-185.

Abstract

Plants from the genus of Pulsatilla produce a variety of secondary metabolites with biological activity. These species play a special role in herbal medicine and are used in traditional folk medicine to treat many diseases and ailments. Due to their numerous medicinal properties, they are now also widely used as homeopathic preparations. In the present study, the antifungal activity of crude extracts of the root of Pulsatilla patens (L.) Mill. against the yeast Candida glabrata with an IC₅₀ of 9.37 μg/mL is reported.

摘要

白头翁属植物产生多种具有生物活性的次生代谢产物。这些物种在草药医学中发挥着特殊作用,并且在传统民间医学中用于治疗多种疾病和不适。由于它们具有众多药用特性,现在它们也被广泛用作顺势疗法制剂。在本研究中,报道了白头翁(Pulsatilla patens (L.) Mill.)根的粗提物对光滑念珠菌的抗真菌活性,其半数抑制浓度(IC₅₀)为9.37μg/mL。

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