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惊恐障碍、社交焦虑障碍和强迫症患者的苯二氮䓬类药物使用的预测因素。

Predictors of benzodiazepine use in a transdiagnostic sample of panic disorder, social anxiety disorder, and obsessive-compulsive disorder patients.

机构信息

Obsessive, Compulsive, and Anxiety Spectrum Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro, Brazil.

Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

出版信息

Psychiatry Res. 2018 Apr;262:237-245. doi: 10.1016/j.psychres.2018.02.013. Epub 2018 Feb 9.

Abstract

We investigated the rates of current and past benzodiazepine (BZD) use in a sample of 102 subjects attending specialized anxiety disorder clinics, including panic disorder (PD; N = 36), social anxiety disorder (SAD; N = 28) and obsessive-compulsive disorder (OCD; N = 38) patients. Almost 56% of the entire sample was using BZDs at the moment of the assessment, and 74.5% described having used them at some point during their lifetimes. The duration of psychiatric treatment and a lifetime history of PD, but not any other "transdiagnostic" measure of severity (such as the Panic and Agoraphobia Scale, the Social Phobia Inventory, the Dimensional Obsessive-Compulsive Scale, the Anxiety Sensitivity Index-36, and the Beck Inventories) were independent risk factors for current prescription of BZDs. Patients who continued to use BZDs differed from patients who stopped them by being older (both currently and when firstly seen in the clinic), by having a later age at onset of their most significant anxiety disorder, by being more agoraphobic/avoidant, and by believing to be less capable of stopping their BZDs for the fear of not being able to sleep.

摘要

我们调查了在 102 名参加专门焦虑症诊所的受试者中,当前和过去苯二氮䓬类药物(BZD)使用的发生率,包括惊恐障碍(PD;N=36)、社交焦虑障碍(SAD;N=28)和强迫症(OCD;N=38)患者。几乎 56%的样本在评估时正在使用 BZD,74.5%的人在他们的一生中曾使用过 BZD。精神科治疗的持续时间和 PD 的终身病史,但不是任何其他“跨诊断”严重程度的衡量标准(如惊恐和广场恐怖症量表、社交恐惧症量表、多维强迫症量表、焦虑敏感指数-36 和贝克量表)是当前 BZD 处方的独立危险因素。继续使用 BZD 的患者与停止使用 BZD 的患者不同,他们年龄更大(现在和首次在诊所就诊时),最严重的焦虑症发病年龄较晚,更恐旷/回避,并且更担心因无法入睡而无法停止使用 BZD 而认为自己能力不足。

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