Mony Tamanna Jahan, Hong Minha, Lee Hee Jae
Department of Pharmacology, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Department of Psychiatry, School of Medicine, Seonam University, Goyang, Republic of Korea.
Psychiatry Investig. 2018 Feb;15(2):104-110. doi: 10.30773/pi.2017.06.20. Epub 2017 Dec 14.
There is a highly cognitive and social context to empathy behavior in human. In various social contexts, rodents also display remarkable affective sensitivity and exhibit primitive forms of empathy similar to human. Therefore, we aimed to elaborate the concept of empathy about various components of empathetic behavior in rodents with the similar contexts of a human. In this review, we highlighted the behavioral paradigm that already examined different aspects of rodent empathetic behavior in response to conspecific distress. Additionally, we summarized homologous brain parts of human and rodents to express the empathetic behavior. Integrating the findings with corresponding experiments in the human will provide a novel insight into therapeutic intervention or expanded experimental approaches for neuropsychiatric disorders like autism spectrum disorders associated with empathetic behavior.
人类的共情行为存在高度认知和社会背景。在各种社会情境中，啮齿动物也表现出显著的情感敏感性，并展现出与人类相似的原始形式的共情。因此，我们旨在在与人类相似的情境下，阐述啮齿动物共情行为各组成部分的共情概念。在这篇综述中，我们重点介绍了已经用于研究啮齿动物对同种痛苦做出反应时共情行为不同方面的行为范式。此外，我们总结了人类和啮齿动物用于表达共情行为的同源脑区。将这些研究结果与人类相应的实验相结合，将为神经精神疾病（如与共情行为相关的自闭症谱系障碍）的治疗干预或扩展实验方法提供新的见解。
