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经椎间盘固定与后路固定联合或不联合经椎间孔腰椎椎间融合术治疗L5-S1腰骶关节的生物力学比较

Biomechanical comparison of transdiscal fixation and posterior fixation with and without transforaminal lumbar interbody fusion in the treatment of L5-S1 lumbosacral joint.

作者信息

Özalp Hakan, Özkaya Mustafa, Yaman Onur, Demir Teyfik

机构信息

1 Department of Neurosurgery, Mersin University, Mersin, Turkey.

2 Department of Mechanical Engineering, KTO Karatay University, Konya, Turkey.

出版信息

Proc Inst Mech Eng H. 2018 Apr;232(4):371-377. doi: 10.1177/0954411918760959. Epub 2018 Feb 23.

Abstract

Transdiscal screw fixation is generally performed in the treatment of high-grade L5-S1 spondylolisthesis. The main thought of the study is that the biomechanical performances of the transdiscal pedicle screw fixation can be identical to standard posterior pedicle screw fixations with or without transforaminal lumbar interbody fusion cage insertion. Lumbosacral portions and pelvises of 45 healthy lambs' vertebrae were dissected. Animal cadavers were randomly and equally divided into three groups for instrumentation. Three fixation systems, L5-S1 posterior pedicle screw fixation, L5-S1 posterior pedicle screw fixation with transforaminal lumbar interbody fusion cage insertion, and L5-S1 transdiscal pedicle screw fixation, were generated. Axial compression, flexion, and torsion tests were conducted on test samples of each system. In axial compression, L5-S1 transdiscal fixation was less stiff than L5-S1 posterior pedicle screw fixation with transforaminal lumbar interbody fusion cage insertion. There were no significant differences between groups in flexion. Furthermore, L5-S1 posterior fixation was stiffest under torsional loads. When axial compression and flexion loads are taken into consideration, transdiscal fixation can be alternatively used instead of posterior pedicle screw fixation in the treatment of L5-S1 spondylolisthesis because it satisfies enough stability. However, in torsion, posterior fixation is shown as a better option due to its higher stiffness.

摘要

经椎间盘螺钉固定术通常用于治疗重度L5 - S1椎体滑脱。该研究的主要观点是,经椎间盘椎弓根螺钉固定术的生物力学性能与标准后路椎弓根螺钉固定术(无论是否插入椎间融合器)相同。对45只健康羔羊的腰椎和骨盆椎体进行了解剖。将动物尸体随机等分为三组进行器械固定。生成了三种固定系统,即L5 - S1后路椎弓根螺钉固定、L5 - S1后路椎弓根螺钉固定并插入椎间融合器以及L5 - S1经椎间盘椎弓根螺钉固定。对每个系统的测试样本进行了轴向压缩、屈曲和扭转试验。在轴向压缩试验中,L5 - S1经椎间盘固定的刚度低于L5 - S1后路椎弓根螺钉固定并插入椎间融合器的情况。在屈曲试验中,各组之间没有显著差异。此外,在扭转载荷下,L5 - S1后路固定的刚度最大。当考虑轴向压缩和屈曲载荷时,经椎间盘固定由于具有足够的稳定性,可替代后路椎弓根螺钉固定用于治疗L5 - S1椎体滑脱。然而,在扭转试验中,后路固定因其更高的刚度而显示为更好的选择。

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