Pfeifer U, Dämmrich J
Basic Res Cardiol. 1986;81 Suppl 1:139-46. doi: 10.1007/978-3-662-11374-5_14.
Ultrastructural evidence is presented that intracellular autophagic degradation of cytoplasmic constituents is reduced during pressure induced hypertrophy of left ventricular myocardium after supravalvular aortic constriction in rats. This anti-catabolic reaction has to be considered as an important mechanism for shifting the balance between synthesis and degradation to the positive side. Short term studies after administration of isoproterenol suggest a close functional relationship between work load on the one hand and the anti-catabolic reaction on the other.
有超微结构证据表明，大鼠主动脉瓣上缩窄后左心室心肌压力诱导性肥大期间，细胞质成分的细胞内自噬降解减少。这种抗分解代谢反应必须被视为将合成与降解之间的平衡转向正向的重要机制。给予异丙肾上腺素后的短期研究表明，一方面工作负荷与另一方面抗分解代谢反应之间存在密切的功能关系。
