Coquard R, N'Guyen A M, Mathis T, Josserand-Pietri F, Khodri M, Largeron G, Barbet N, Grange J D
Centre de radiothérapie Bayard, 44, avenue Condorcet, 69100 Villeurbanne, France.
Service d'ophtalmologie, hôpital de la Croix-Rousse, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France.
Cancer Radiother. 2018 Apr;22(2):107-111. doi: 10.1016/j.canrad.2017.08.111. Epub 2018 Feb 21.
To evaluate the results of an adjuvant contact irradiation using 50kV photons after resection of conjunctival malignancies.
From 2012 to 2014, 14 patients (male: nine; female: five) have been treated by contact irradiation after resection of a malignant tumor of the conjunctiva (melanoma: five patients; malignant fibrous histiocytoma: one patient; carcinoma: eight patients) The treatment was performed using the Papillon 50 machine (Ariane). Three to four sessions were delivered, each giving a dose of 10Gy. The median follow-up in survivors was 33 months.
The tolerance was good. A cataract was seen in one patient, and a moderate eye dryness in one. There was no corneal ulcer. One patient died of intercurrent disease. One patient with carcinoma recurred locally.
Adjuvant contact radiotherapy provides a good local control after resection of conjunctival malignancies (melanoma, malignant histiocytofibroma, carcinoma). Thanks to its precision, this technique is well tolerated with a low rate of complications. Furthermore, it is delivered on an ambulatory basis.