Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea.
Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea.
J Hosp Infect. 2018 Aug;99(4):487-491. doi: 10.1016/j.jhin.2018.02.017. Epub 2018 Feb 21.
A 10-month active surveillance study was conducted to assess carriage of carbapenemase-producing Enterobacteriaceae (CPE), vancomycin-resistant enterococci (VRE) and toxigenic Clostridium difficile colonization among patients transferred to hospital from long-term care facilities (LTCFs). Four (1.4%) patients with carbapenem-resistant Enterobacteriaceae (none of which were CPE), 59 (21%) patients with VRE and 20 (7.1%) patients colonized with toxigenic C. difficile were identified from 282 rectal specimens. There was no outbreak of VRE infection during the study period. The low prevalence of CPE carriage suggests that screening all admissions from LTCFs for CPE would not be cost-effective, and that screening and use of contact precautions for VRE should be reconsidered.
一项为期 10 个月的主动监测研究旨在评估从长期护理机构（LTCFs）转入医院的患者中产碳青霉烯酶肠杆菌科（CPE）、耐万古霉素肠球菌（VRE）和产毒艰难梭菌定植的情况。从 282 份直肠标本中鉴定出 4 例（1.4%）碳青霉烯类耐药肠杆菌科（无 CPE）、59 例（21%）VRE 和 20 例（7.1%）产毒艰难梭菌定植的患者。在研究期间没有发生 VRE 感染的暴发。CPE 携带率较低表明，对所有从 LTCFs 转入的患者进行 CPE 筛查没有经济效益，应该重新考虑对 VRE 进行筛查和使用接触预防措施。
