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磁共振成像禁忌时计算机断层扫描脑池造影术在三叉神经痛评估中的应用:病例报告及文献综述

Computed Tomography Cisternography for Evaluation of Trigeminal Neuralgia When Magnetic Resonance Imaging Is Contraindicated: Case Report and Review of the Literature.

作者信息

Gospodarev Vadim, Chakravarthy Vikram, Harms Casey, Myers Hannah, Kaplan Brett, Kim Esther, Pond Matthew, De Los Reyes Kenneth

机构信息

Loma Linda University School of Medicine, Loma Linda, California, USA.

Department of Neurosurgery, LLUMC, Loma Linda, California, USA.

出版信息

World Neurosurg. 2018 May;113:180-183. doi: 10.1016/j.wneu.2018.02.066. Epub 2018 Feb 21.

Abstract

BACKGROUND

Trigeminal neuralgia (TGN) causes severe unilateral facial pain. The etiology is hypothesized to be segmental demyelination of the trigeminal nerve root via compression by the superior cerebellar artery (SCA). Microvascular decompression (MVD) allows immediate and long-term pain relief. Preoperative evaluation includes magnetic resonance imaging (MRI) and/or magnetic resonance angiography of the brain. Having a pacemaker is a contraindication for MRI. There have been isolated reports of using computed tomography (CT) cisternography scans for radiation planning for TGN.

CASE DESCRIPTION

A 75-year-old male with a permanent pacemaker who had refractory TGN in the V2 (maxillary) distribution of the trigeminal nerve underwent CT cisternography to prepare for MVD. CT angiography with Isovue 370 intravenous contrast injection and 0.625-mm axial images were obtained from the skull base across the posterior fossa. An intrathecal injection of Isovue 180 was performed at the L2/3 level. Imaging revealed the right SCA abutting the medial margin of the proximal right trigeminal nerve. In surgery (K.D.), a standard retrosigmoid suboccipital craniotomy was performed to access the cerebellopontine angle and separate the abutting SCA and trigeminal nerve. The patient had immediate pain relief.

CONCLUSIONS

MRI is the preferred method of evaluating for TGN because it offers excellent visualization of vasculature in relation to the trigeminal nerve without accompanying radiation exposure. However, for patients who have contraindications to MRI, CT cisternography is shown to also be an effective method for visualizing the trigeminal root entry zone and nearby vasculature in preparation for MVD of the trigeminal nerve.

摘要

背景

三叉神经痛(TGN)会导致严重的单侧面部疼痛。其病因被认为是三叉神经根通过小脑上动脉(SCA)压迫导致节段性脱髓鞘。微血管减压术(MVD)可实现即刻和长期的疼痛缓解。术前评估包括脑部磁共振成像(MRI)和/或磁共振血管造影。装有起搏器是MRI的禁忌证。已有关于使用计算机断层扫描(CT)脑池造影扫描进行TGN放射治疗计划的个别报道。

病例描述

一名75岁男性,装有永久性起搏器,三叉神经V2(上颌支)分布区患有难治性TGN,接受了CT脑池造影以准备进行MVD。通过静脉注射碘海醇370进行CT血管造影,并从颅底至后颅窝获取0.625毫米的轴向图像。在L2/3水平进行了鞘内注射碘海醇1捌。成像显示右侧SCA紧靠右侧三叉神经近端的内侧边缘。在手术中(K.D.),进行了标准的乙状窦后枕下开颅术,以进入桥小脑角并分离紧靠的SCA和三叉神经。患者疼痛即刻缓解。

结论

MRI是评估TGN的首选方法,因为它能很好地显示与三叉神经相关的血管系统,且无辐射暴露。然而,对于有MRI禁忌证的患者,CT脑池造影也被证明是一种有效的方法,可用于在准备三叉神经MVD时可视化三叉神经根入区及附近血管系统。

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