脂肪组织和毛发功能：一种明显的关联。
Adipose and Hair Function: An aPPARent Connection.
机构信息
Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
出版信息
J Invest Dermatol. 2018 Mar;138(3):480-482. doi: 10.1016/j.jid.2017.10.019.
Abstract
Adipose tissue plays essential roles in various aspects of skin physiology, from regulating hair follicle morphogenesis to wound healing. Peroxisome proliferator-activated receptor gamma is important for the maintenance of adipose tissue and has been implicated in some types of hair loss; however, its function during the hair cycle is still unclear. Sardella et al. investigate the role of peroxisome proliferator-activated receptor gamma in hair follicle morphogenesis using a novel global peroxisome proliferator-activated receptor gamma-null mouse.
摘要
脂肪组织在皮肤生理学的各个方面发挥着重要作用，从调节毛囊形态发生到伤口愈合。过氧化物酶体增殖物激活受体γ对于维持脂肪组织很重要，并且与某些类型的脱发有关；然而，其在毛发周期中的功能尚不清楚。Sardella 等人使用新型的全局过氧化物酶体增殖物激活受体γ 敲除小鼠研究过氧化物酶体增殖物激活受体γ在毛囊形态发生中的作用。
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