Oshyvalova Olena O, Kaliuzhna Lydia D, Kropelnytskyi Vladislav O
Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, State Scientific Institution "Research and Practical Centre of Preventive and Clinical Medicine" of the State Administration, Kyiv, Ukraine.
Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine.
Wiad Lek. 2017;70(6 pt 1):1072-1078.
Introduction: Actinic keratosis (AK) is precancerous skin lesion that occurs in the sun-exposedskin areas characterized by local intraepidermal dysplasia of different severity (KIN I, KIN II and KIN III). The aim of this research was to study distribution patterns and morphological features of AK histological types.
Materials and Methods: The study included skin biopsy material from 68 patients with different clinical forms of AK. The diagnosis of AK was histologically confirmed in 100% of cases.
Results: There were 63.21% of men and 36.8% of women among all patients with AK. The average age of patients was 73.3 ± 8.3.The most common clinico-histological forms of actinic keratosis were typical (41.2%), hypertrophic (16.2%), atrophic (14.7%) and pigmentary (11.7%), bowenoid (8.8%), acantholytic (7.4%). Among the rate of epidermal dysplasia there diagnosed cases of KIN І (50%), KIN ІІ (36.8%) and KIN III (13.2%).
Conclusions: It was found a direct correlation between KIN I and typical and pigment forms of AK, KIN II and hypertrophic and bowenoid forms of AK.
引言：光化性角化病（AK）是一种癌前皮肤病变，发生于阳光暴露部位，其特征为不同严重程度的局部表皮发育异常（KIN I、KIN II和KIN III）。本研究的目的是研究AK组织学类型的分布模式和形态学特征。
材料与方法：本研究纳入了68例不同临床形式AK患者的皮肤活检材料。所有病例经组织学确诊为AK。
结果：所有AK患者中男性占63.21%，女性占36.8%。患者的平均年龄为73.3±8.3岁。光化性角化病最常见的临床组织学形式为典型型（41.2%）、肥厚型（16.2%）、萎缩型（14.7%）和色素型（11.7%）、鲍温样型（8.8%）、棘层松解型（7.4%）。在表皮发育异常率中，诊断出KIN І病例（50%）、KIN ІІ病例（36.8%）和KIN III病例（13.2%）。
结论：发现KIN I与典型和色素型AK、KIN II与肥厚型和鲍温样型AK之间存在直接相关性。
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