Preparing cuprous oxide nanomaterials by electrochemical method for non-enzymatic glucose biosensor.

Cuprous oxide (CuO) nanostructure has been synthesized using an electrochemical method with a two-electrode system. Cu foils were used as electrodes and NH(OH) was utilized as the reducing agent. The effects of pH and applied voltages on the morphology of the product were investigated. The morphology and optical properties of CuO particles were characterized using scanning electron microscopy, x-ray diffraction, and diffuse reflectance spectra. The synthesized CuO nanostructures that formed in the vicinity of the anode at 2 V and pH = 11 showed high uniform distribution, small size, and good electrochemical sensing. These CuO nanoparticles were coated on an Indium tin oxide substrate and applied to detect non-enzyme glucose as excellent biosensors. The non-enzyme glucose biosensors exhibited good performance with high response, good selectivity, wide linear detection range, and a low detection limit at 0.4 μM. Synthesized CuO nanostructures are potential materials for a non-enzyme glucose biosensor.