O'Neill P A, Levy B M
J Med Primatol. 1986;15(6):409-17.
T lymphocytes were studied in healthy young and old marmosets (Callithrix jacchus). Data indicate that monoclonal antisera to human T lymphocyte antigens can be used to identify these cells in marmosets. Total T and suppressor T cells were lower in the older group; there were no differences in helper T or in B cells. Helper/suppressor ratios (T4/T8) were increased in the older group. Thus, immune system alternations with aging and/or immune deficiency syndromes may be studied in this animal model using available reagents.
对健康的幼年和老年狨猴（普通狨）的T淋巴细胞进行了研究。数据表明，针对人类T淋巴细胞抗原的单克隆抗血清可用于识别狨猴体内的这些细胞。老年组的总T细胞和抑制性T细胞数量较低；辅助性T细胞或B细胞无差异。老年组的辅助/抑制比值（T4/T8）升高。因此，利用现有试剂，可在该动物模型中研究衰老和/或免疫缺陷综合征导致的免疫系统变化。
