Garcia-Madrona S, Corral-Corral I
Hospital Universitario Ramon y Cajal, 28034 Madrid, Espana.
Rev Neurol. 2018 Mar 1;66(5):154-156.
Occipital condyle syndrome consists of the presence of unilateral occipital headache exacerbated by moving the head and is accompanied by paralysis of the ipsilateral hypoglossal nerve. One of its causes is infiltration of the base of the skull by bone metastases, especially those affecting the hypoglossal nerve due to infiltration as it passes through the osseous canal.
We report two clinical cases of occipital condyle syndrome secondary to metastatic hepatocarcinoma. The first is that of a 52-year-old male with liver cirrhosis secondary to liver pathology caused by hepatitis C virus with occipital condyle syndrome as the presenting symptom in disseminated hepatocarcinoma. The second case is that of a 56-year-old male after recurrence of hepatocarcinoma following a liver transplant, despite not fulfilling the Milan criteria.
Occipital condyle syndrome is an alarm symptom and requires a thorough study by means of imaging tests, since it may be the first symptom of an undetected hepatocarcinoma.
枕髁综合征表现为头部活动时单侧枕部头痛加剧,并伴有同侧舌下神经麻痹。其病因之一是骨转移瘤浸润颅骨底部,尤其是当舌下神经穿过骨性管道时因浸润而受影响。
我们报告两例继发于转移性肝癌的枕髁综合征临床病例。第一例是一名52岁男性,患有丙型肝炎病毒引起的肝脏病变继发肝硬化,在播散性肝癌中以枕髁综合征为首发症状。第二例是一名56岁男性,在肝移植后肝癌复发,尽管不符合米兰标准。
枕髁综合征是一种警示症状,需要通过影像学检查进行全面评估,因为它可能是未被发现的肝癌的首发症状。