通过旋转框架下的自旋锁定对比T1弛豫（T1ρ）MRI识别胶质母细胞瘤内具有生物学侵袭性的区域。
Biologically aggressive regions within glioblastoma identified by spin-lock contrast T1 relaxation in the rotating frame (T1ρ) MRI.
作者信息
Barajas Ramon Francisco, Villanueva-Meyer Javier, Perry Arie, Berger Mitchel, Cha Soonmee
机构信息
Department of Radiology, Oregon Health and Science University, Portland, OR.
Advanced Imaging Research Center, Oregon Health and Science University, Portland, OR.
出版信息
Radiol Case Rep. 2017 Sep 1;12(4):827-832. doi: 10.1016/j.radcr.2017.07.010. eCollection 2017 Dec.
Spin-lattice relaxation in the rotating frame magnetic resonance imaging allows for the quantitative assessment of spin-lock contrast within tissues. We describe the utility of spin-lattice relaxation in the rotating frame metrics in characterizing glioblastoma biological heterogeneity. A 84-year-old man presented to our institution with a right frontal temporal mass. Prior tissue sampling from a peripheral nonenhancing lesion was nondiagnostic. Stereotactic image-guided tissue sampling of the nonenhancing T2-fluid-attenuated inversion recovery hyperintense region involving the anterior cingulate gyrus with elevated spin-lattice relaxation in the rotating frame metrics provided a pathologic diagnosis of glioblastoma. This case illustrates the utility of spin-lattice relaxation in the rotating frame magnetic resonance imaging in identifying biologically aggressive regions within glioblastoma.
旋转框架磁共振成像中的自旋晶格弛豫可用于定量评估组织内的自旋锁定对比度。我们描述了旋转框架度量中的自旋晶格弛豫在表征胶质母细胞瘤生物学异质性方面的效用。一名84岁男性因右额颞部肿块就诊于我院。先前对周边非强化病变进行的组织采样未得出诊断结果。对涉及前扣带回的非强化T2液体衰减反转恢复高信号区域进行立体定向图像引导组织采样，该区域在旋转框架度量中具有升高的自旋晶格弛豫，从而得出胶质母细胞瘤的病理诊断。该病例说明了旋转框架磁共振成像中的自旋晶格弛豫在识别胶质母细胞瘤内生物学侵袭性区域方面的效用。
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