Fukuda Akinari, Sakamoto Seisuke, Sasaki Kengo, Narumoto Soichi, Kitajima Toshihiro, Hirata Yoshihiro, Hishiki Tomoro, Kasahara Mureo
Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Pediatr Transplant. 2018 May;22(3):e13167. doi: 10.1111/petr.13167. Epub 2018 Apr 1.
HVOO can be a critical complication in pediatric LDLT. The aim of this study was to evaluate a modified triangular technique of hepatic vein reconstruction for preventing HVOO in pediatric LDLT. A total of 298 pediatric LDLTs were performed using a left lateral segment graft by 2 methods for reconstruction of the hepatic vein. In 177 recipients, slit-shaped anastomosis was indicated with partial clamp of the IVC. A total of 121 recipients subjected to the modified triangular anastomosis with total clamp of the IVC. We compared the incidence of hepatic vein anastomotic complications between these 2 methods. Nine of the 177 cases (5.3%) treated with the conventional technique were diagnosed with outflow obstruction. All 9 cases underwent hepatic vein reconstruction with the slit-shaped hepatic vein anastomosis. In contrast, there were no cases of outflow obstruction in the 121 cases treated with the modified triangular anastomosis. The modified triangular technique of hepatic vein reconstruction with total clamping of the IVC was useful for preventing HVOO in pediatric LDLT.
肝静脉流出道梗阻(HVOO)可能是小儿活体肝移植(LDLT)中的一种严重并发症。本研究的目的是评估一种改良的三角形肝静脉重建技术,以预防小儿LDLT中的HVOO。共有298例小儿LDLT采用左外叶 graft,通过两种方法重建肝静脉。在177例受者中,采用下腔静脉部分阻断进行裂隙状吻合。共有121例受者接受改良三角形吻合,同时完全阻断下腔静脉。我们比较了这两种方法之间肝静脉吻合并发症的发生率。采用传统技术治疗的177例患者中有9例(5.3%)被诊断为流出道梗阻。所有9例均采用裂隙状肝静脉吻合进行肝静脉重建。相比之下,采用改良三角形吻合治疗的121例患者中没有出现流出道梗阻的病例。完全阻断下腔静脉的改良三角形肝静脉重建技术有助于预防小儿LDLT中的HVOO。