• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

1-棕榈酰-2-(对苯甲酰基)苯甲酰磷脂酰胆碱,一种用于标记膜成分的光活性磷脂。

1-Palmitoyl-2-(p-benzoyl)benzoyl phosphatidylcholine, a photoactive phospholipid for the labelling of membrane components.

作者信息

Montecucco C, Schiavo G

出版信息

Biochem J. 1986 Jul 1;237(1):309-12. doi: 10.1042/bj2370309.

DOI:10.1042/bj2370309
PMID:2948491
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1146985/
Abstract

The preparation and use of a new photoactivatable phosphatidylcholine derivative [1-palmitoyl-2-(p-benzoyl)benzoyl phosphatidylcholine] is described. The reagent is shown to be effective in labelling different membrane proteins under irradiation conditions that preserve their enzymic activity. The properties of this new phospholipid analogue suggest that it can be useful in studying several aspects of membrane structure and function.

摘要

本文描述了一种新型光可激活磷脂酰胆碱衍生物[1-棕榈酰-2-(对苯甲酰基)苯甲酰磷脂酰胆碱]的制备和应用。结果表明,该试剂在能保持其酶活性的辐照条件下,对不同膜蛋白的标记有效。这种新型磷脂类似物的特性表明,它在研究膜结构和功能的多个方面可能有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18ea/1146985/6564e9b1d006/biochemj00276-0300-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18ea/1146985/6564e9b1d006/biochemj00276-0300-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18ea/1146985/6564e9b1d006/biochemj00276-0300-a.jpg

相似文献

1
1-Palmitoyl-2-(p-benzoyl)benzoyl phosphatidylcholine, a photoactive phospholipid for the labelling of membrane components.1-棕榈酰-2-(对苯甲酰基)苯甲酰磷脂酰胆碱,一种用于标记膜成分的光活性磷脂。
Biochem J. 1986 Jul 1;237(1):309-12. doi: 10.1042/bj2370309.
2
[Reparation of hepatocyte mitochondrial membranes using phosphatidylcholine liposomes].[利用磷脂酰胆碱脂质体修复肝细胞线粒体膜]
Biull Eksp Biol Med. 1991 Aug;112(8):135-6.
3
Synthesis and in vitro antioxidant and antimicrobial studies of novel structured phosphatidylcholines with phenolic acids.新型结构的含酚酸磷脂酰胆碱的合成及其体外抗氧化和抗菌研究
Food Chem. 2017 Apr 15;221:664-672. doi: 10.1016/j.foodchem.2016.11.121. Epub 2016 Nov 25.
4
Rapid formation of 4-hydroxy-2-nonenal, malondialdehyde, and phosphatidylcholine aldehyde from phospholipid hydroperoxide by hemoproteins.血红素蛋白促使磷脂氢过氧化物快速形成4-羟基-2-壬烯醛、丙二醛和磷脂酰胆碱醛。
Free Radic Biol Med. 2004 Apr 15;36(8):1025-33. doi: 10.1016/j.freeradbiomed.2004.01.006.
5
Photolabelling of membrane proteins with photoactive phospholipids.用光敏磷脂对膜蛋白进行光标记。
Biochem J. 1981 Mar 1;193(3):757-63. doi: 10.1042/bj1930757.
6
Phospholipid-protein adducts of lipid peroxidation: synthesis and study of new biotinylated phosphatidylcholines.脂质过氧化的磷脂-蛋白质加合物:新型生物素化磷脂酰胆碱的合成与研究
Chem Res Toxicol. 2007 Feb;20(2):227-34. doi: 10.1021/tx600331s.
7
Synthesis and properties of a fluorescent derivative of phosphatidylcholine.磷脂酰胆碱荧光衍生物的合成与性质
Life Sci. 1977 Aug 1;21(3):345-55. doi: 10.1016/0024-3205(77)90515-x.
8
Photocrosslinking and click chemistry enable the specific detection of proteins interacting with phospholipids at the membrane interface.光交联和点击化学能够特异性检测在膜界面与磷脂相互作用的蛋白质。
Chem Biol. 2009 Jan 30;16(1):3-14. doi: 10.1016/j.chembiol.2008.11.009.
9
[The erythrocyte membrane. I- Properties under normal conditions].[红细胞膜。I - 正常条件下的特性]
Nouv Presse Med. 1977 Mar 26;6(12):1041-4.
10
Erythrocyte phospholipid organization and vesiculation in hereditary high red cell membrane phosphatidylcholine hemolytic anemia.遗传性高红细胞膜磷脂酰胆碱溶血性贫血中的红细胞磷脂组织与囊泡形成
J Lab Clin Med. 1989 Mar;113(3):278-84.

引用本文的文献

1
Erythrocyte morphology reflects the transbilayer distribution of incorporated phospholipids.红细胞形态反映了掺入磷脂的跨膜分布。
J Cell Biol. 1989 Apr;108(4):1375-85. doi: 10.1083/jcb.108.4.1375.

本文引用的文献

1
A SIMPLE, SPECIFIC SPRAY FOR THE DETECTION OF PHOSPHOLIPIDS ON THIN-LAYER CHROMATOGRAMS.一种用于检测薄层色谱图上磷脂的简单、特效喷雾剂。
J Lipid Res. 1964 Jan;5:126-7.
2
Phosphorus assay in column chromatography.柱色谱法中的磷测定
J Biol Chem. 1959 Mar;234(3):466-8.
3
Exploring the adenine nucleotide binding sites on mitochondrial F1-ATPase with a new photoaffinity probe, 3'-O-(4-benzoyl)benzoyl adenosine 5'-triphosphate.用新型光亲和探针3'-O-(4-苯甲酰基)苯甲酰腺苷5'-三磷酸探索线粒体F1-ATP酶上的腺嘌呤核苷酸结合位点。
J Biol Chem. 1982 Mar 25;257(6):2834-41.
4
Membrane topology of ATP synthase from bovine heart mitochondria and Escherichia coli.
Eur J Biochem. 1983 Apr 15;132(1):189-94. doi: 10.1111/j.1432-1033.1983.tb07346.x.
5
Labeling of subunit b of the ATP synthase from Escherichia coli with a photoreactive phospholipid analogue.用一种光反应性磷脂类似物对大肠杆菌ATP合酶的亚基b进行标记。
J Biol Chem. 1983 Mar 10;258(5):2882-5.
6
Photolabelling of membrane proteins with photoactive phospholipids.用光敏磷脂对膜蛋白进行光标记。
Biochem J. 1981 Mar 1;193(3):757-63. doi: 10.1042/bj1930757.
7
Labelling of the hydrophobic domain of the Na+,K+-ATPase.钠钾ATP酶疏水结构域的标记
FEBS Lett. 1981 Jun 1;128(1):17-21. doi: 10.1016/0014-5793(81)81068-x.
8
Photochemical probes of the active site of myosin. Irradiation of trapped 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate labels the 50-kilodalton heavy chain tryptic peptide.肌球蛋白活性位点的光化学探针。对捕获的3'-O-(4-苯甲酰基)苯甲酰腺苷5'-三磷酸进行辐照,可标记50千道尔顿重链胰蛋白酶肽段。
J Biol Chem. 1984 Nov 10;259(21):12956-9.
9
Localization of the high-affinity binding site for ATP on the membrane-bound chloroplast ATP synthase.ATP在膜结合叶绿体ATP合酶上高亲和力结合位点的定位。
J Biol Chem. 1984 Oct 10;259(19):12271-8.
10
Structure of the membrane-embedded F0 part of F1F0 ATP synthase from Escherichia coli as inferred from labeling with 3-(Trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine.通过用3-(三氟甲基)-3-(间-[¹²⁵I]碘苯基)重氮甲烷标记推断出的来自大肠杆菌的F₁F₀ATP合酶膜嵌入F₀部分的结构
Biochemistry. 1984 Nov 6;23(23):5610-6. doi: 10.1021/bi00318a035.