Quera Rodrigo, Flores Lilian, Simian Daniela, Kronberg Udo, Vial María Teresa, de Guevara David Ladrón, García-Rodríguez María José
Clínica Las Condes, Santiago, Chile.
Servicio de Anatomía Patológica, Clínica Las Condes, Santiago, Chile.
Rev Med Chil. 2017 Oct;145(10):1342-1348. doi: 10.4067/S0034-98872017001001342.
Primary colorectal lymphoma is a rare form of presentation of gastrointestinal tract lymphomas. Inflammatory bowel disease and its treatment are risk factors for its development. We report a 47-year-old male patient with Ulcerative Colitis of two years of evolution, treated initially with azathioprine and later on with infliximab. Due to a relapse in symptoms after the second dose of infliximab, a new coloncoscopy was performed showing a rectal ulcerative lesion, corresponding to a large cell Non-Hodgkin's Lymphoma. The patient was successfully treated with RCHOP chemotherapy (Rituximab cyclophosphamide doxorubicin vincristine prednisone). He is currently in disease remission.
原发性结直肠淋巴瘤是胃肠道淋巴瘤的一种罕见表现形式。炎症性肠病及其治疗是其发生的危险因素。我们报告一名47岁男性患者，患有病程两年的溃疡性结肠炎，最初用硫唑嘌呤治疗，后来用英夫利昔单抗治疗。由于第二次注射英夫利昔单抗后症状复发，进行了一次新的结肠镜检查，发现直肠有溃疡性病变，确诊为大细胞非霍奇金淋巴瘤。该患者接受RCHOP化疗（利妥昔单抗、环磷酰胺、多柔比星、长春新碱、泼尼松）治疗成功。他目前处于疾病缓解期。
