Timmis A D, Griffin B, Crick J C, Sowton E
Int J Cardiol. 1987 Jan;14(1):25-31. doi: 10.1016/0167-5273(87)90175-6.
This report describes the results of percutaneous transluminal coronary angioplasty in 56 patients with unstable angina. In each case diagnostic coronary angiography had demonstrated a critical proximal stenosis in a major vessel. The stenosis was successfully dilated without complication in 70% of cases. Angiographic success was reflected by the abolition of symptoms and a nonischaemic predischarge stress test in 82 and 72% of cases, respectively. Importantly, at six months follow-up 69% of these patients remained symptom free though repeat angioplasty had been necessary in 21% of cases. The in-hospital incidence of myocardial infarction and death was 7.1 and 5.4%, respectively, but during the six month follow-up period only one additional complicating event occurred. Results were particularly favourable in patients with single vessel disease, 83% of whom had successful procedures. There was one uncomplicated myocardial infarct in this subgroup but no deaths. These data indicate that percutaneous transluminal coronary angioplasty may be undertaken with relative safety in patients with unstable angina and leads to a substantial improvement in symptoms that is sustained during early follow up. The benefits of this therapeutic approach may be particularly marked in patients with single vessel disease.
本报告描述了56例不稳定型心绞痛患者经皮腔内冠状动脉成形术的结果。在每例患者中，诊断性冠状动脉造影均显示主要血管近端存在严重狭窄。70%的病例中狭窄成功扩张且无并发症。分别有82%和72%的病例症状消失且出院前应激试验无缺血表现，反映了血管造影术的成功。重要的是，在六个月的随访中，69%的患者无症状，尽管21%的病例需要再次进行血管成形术。住院期间心肌梗死和死亡的发生率分别为7.1%和5.4%，但在六个月的随访期内仅发生了1例额外的并发症事件。单支血管病变患者的结果尤为良好，其中83%的患者手术成功。该亚组中有1例无并发症的心肌梗死，但无死亡病例。这些数据表明，不稳定型心绞痛患者进行经皮腔内冠状动脉成形术可能相对安全，并能使症状在早期随访期间得到显著改善。这种治疗方法的益处可能在单支血管病变患者中尤为明显。
