Fassina A, Rubinacci A, Tessari L
Int J Clin Pharmacol Res. 1986;6(6):501-7.
The measurement of diastasis of the spinous processes and of muscular action potentials by means of bio-feedback equipment is a clinically valid means to evaluate the extent of reflex muscular contracture. The methods were used to study the relaxant effect of pridinol mesylate on the lumbar extensor muscles in subjects with acute low back pain. It was found that pridinol mesylate significantly reduced the contracture of the extensor lumbar muscles in low back pain when given per os or parenterally.
通过生物反馈设备测量棘突间距离和肌肉动作电位是评估反射性肌肉挛缩程度的一种临床有效方法。这些方法被用于研究甲磺酸普立地诺对急性下背痛患者腰部伸肌的松弛作用。结果发现，口服或胃肠外给予甲磺酸普立地诺时，其能显著减轻下背痛患者腰部伸肌的挛缩。
