Issa Ghada, Davis Derik, Mulligan Michael E
J Comput Assist Tomogr. 2018 Jul/Aug;42(4):552-558. doi: 10.1097/RCT.0000000000000722.
The objective of this study was to determine if dual-energy computed-tomography bone marrow color maps can improve sensitivity, specificity, accuracy, and confidence of detection of bone metastases.
Institutional review board approved this retrospective review of a consecutive series of cancer patients. Two radiologists first evaluated the fused 120 kV computed tomography images and recorded a number of suspicious lesions, confidence level, and Hounsfield units for each lesion. After a time gap, the studies were randomized for a second review with dual-energy computed-tomography bone marrow color maps.
Eighteen patients and 1105 bones were reviewed. A total of 227 true metastatic lesions were present. With bone marrow color map review, sensitivity increased from 76.2% to 86.8%, for reader 1, and from 80.2% to 92.8%, for reader 2. Specificity and accuracy also increased. Confidence level increased for 12 lesions.
Dual-energy computed-tomography bone marrow color map analysis of patients with metastatic cancers can improve the sensitivity, specificity, accuracy, and confidence level for the detection of bone metastases.
本研究的目的是确定双能计算机断层扫描骨髓彩色图谱是否能提高骨转移检测的敏感性、特异性、准确性和可信度。
机构审查委员会批准了对一系列连续癌症患者的回顾性研究。两名放射科医生首先评估融合的120 kV计算机断层扫描图像，并记录每个病变的可疑病变数量、置信水平和亨氏单位。经过一段时间间隔后，将研究随机进行第二次双能计算机断层扫描骨髓彩色图谱审查。
对18名患者和1105块骨骼进行了审查。共有227个真正的转移病变。对于读者1，通过骨髓彩色图谱审查，敏感性从76.2%提高到86.8%，对于读者2，从80.2%提高到92.8%。特异性和准确性也有所提高。12个病变的置信水平提高。
对转移性癌症患者进行双能计算机断层扫描骨髓彩色图谱分析可提高骨转移检测的敏感性、特异性、准确性和置信水平。
