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唑吡坦诱发的喷嚏：阳性再激发的病例报告

Zolpidem-induced sneezing: A case report of positive rechallenge.

作者信息

Amraei Razie, Parsa Abdolhamid, Babaeian Mohammad

机构信息

Shahid Behshti University of Medical Sciences, Tehran, Iran.

出版信息

Medicine (Baltimore). 2018 Mar;97(9):e9918. doi: 10.1097/MD.0000000000009918.

DOI:10.1097/MD.0000000000009918
PMID:29489694
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5851732/
Abstract

INTRODUCTION

Zolpidem, as an imidazopyridine, is a widely prescribed drug in clinical practice for short-term treatment of insomnia. Nevertheless, there have been a number of cases associated with the adverse effects of the stated drug recently. Further to the existing reports of adverse reactions to zolpidem, the current script is going to report a case in which zolpidem has induced acute repetitive sneezes.

CONCLUSIONS

A high dose of zolpidem may contribute to interruption to the neurons function involved in the sneezing pathway.

摘要

引言

唑吡坦作为一种咪唑并吡啶类药物，是临床实践中广泛用于短期治疗失眠的药物。然而，最近出现了一些与该药物不良反应相关的病例。继现有的唑吡坦不良反应报告之后，本病例报告将呈现一例唑吡坦诱发急性反复打喷嚏的病例。

结论

高剂量的唑吡坦可能会干扰参与打喷嚏途径的神经元功能。

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引用本文的文献

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Zolpidem-induced sneezing: A case report of positive rechallenge: Erratum.唑吡坦诱发的喷嚏：阳性再激发病例报告：勘误
Medicine (Baltimore). 2018 May;97(19):e0749. doi: 10.1097/MD.0000000000010749.

本文引用的文献

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Zolpidem abuse and dependency in an elderly patient with major depressive disorder: a case report.老年抑郁症患者滥用及依赖唑吡坦：病例报告。
Daru. 2014 Jul 10;22(1):54. doi: 10.1186/2008-2231-22-54.
2
Zolpidem-induced Hallucinations: A Brief Case Report from the Indian Subcontinent.唑吡坦所致幻觉：来自印度次大陆的一则简短病例报告。
Indian J Psychol Med. 2013 Apr;35(2):212-3. doi: 10.4103/0253-7176.116260.
3
Two cases of zolpidem-associated homicide.两例与唑吡坦相关的杀人案件。
Prim Care Companion CNS Disord. 2012;14(4). doi: 10.4088/PCC.12br01363. Epub 2012 Aug 23.
4
Circadian dysregulation, zolpidem dependence, and withdrawal seizure in a resident physician performing shift work.一名从事轮班工作的住院医师出现昼夜节律失调、唑吡坦依赖和戒断性癫痫发作。
Am J Addict. 2012 Nov-Dec;21(6):576-7. doi: 10.1111/j.1521-0391.2012.00273.x. Epub 2012 Sep 21.
5
Desensitization of GABAergic receptors as a mechanism of zolpidem-induced somnambulism.GABA 能受体脱敏作为佐匹克隆诱导梦游的机制。
Med Hypotheses. 2011 Aug;77(2):230-3. doi: 10.1016/j.mehy.2011.04.019. Epub 2011 May 11.
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Adverse reactions to zolpidem: case reports and a review of the literature.唑吡坦的不良反应：病例报告及文献综述
Prim Care Companion J Clin Psychiatry. 2010;12(6). doi: 10.4088/PCC.09r00849bro.
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Sneeze related area in the medulla: localisation of the human sneezing centre?延髓中与喷嚏相关的区域：人类喷嚏中枢的定位？
J Neurol Neurosurg Psychiatry. 2006 Apr;77(4):559-61. doi: 10.1136/jnnp.2005.068601. Epub 2005 Dec 14.
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Relative abuse liability of hypnotic drugs: a conceptual framework and algorithm for differentiating among compounds.催眠药物的相对滥用可能性：区分不同化合物的概念框架和算法
J Clin Psychiatry. 2005;66 Suppl 9:31-41.
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Zolpidem: a review of its use in the management of insomnia.唑吡坦：失眠治疗应用综述
CNS Drugs. 2005;19(1):65-89. doi: 10.2165/00023210-200519010-00008.
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Four aspects of trigeminal nucleus and a paradox.三叉神经核的四个方面及一个悖论。
J Neurophysiol. 1962 Jan;25:110-26. doi: 10.1152/jn.1962.25.1.110.