Petersen Christian Rosenberg, Prtljaga Nikola, Farries Mark, Ward Jon, Napier Bruce, Lloyd Gavin Rhys, Nallala Jayakrupakar, Stone Nick, Bang Ole
Opt Lett. 2018 Mar 1;43(5):999-1002. doi: 10.1364/OL.43.000999.
We present, to the best of our knowledge, the first demonstration of mid-infrared supercontinuum (SC) tissue imaging at wavelengths beyond 5 μm using a fiber-coupled SC source spanning 2-7.5 μm. The SC was generated in a tapered large-mode-area chalcogenide photonic crystal fiber in order to obtain broad bandwidth, high average power, and single-mode output for diffraction-limited imaging performance. Tissue imaging was demonstrated in transmission at selected wavelengths between 5.7 (1754 cm) and 7.3 μm (1370 cm) by point scanning over a sub-millimeter region of colon tissue, and the results were compared to images obtained from a commercial instrument.
据我们所知，我们首次展示了使用覆盖2 - 7.5μm的光纤耦合超连续谱（SC）源在波长超过5μm时进行中红外超连续谱（SC）组织成像。该超连续谱在锥形大模面积硫系光子晶体光纤中产生，以获得宽带宽、高平均功率和单模输出，实现衍射极限成像性能。通过对结肠组织亚毫米区域进行点扫描，在5.7（1754 cm）至7.3μm（1370 cm）的选定波长下进行透射组织成像，并将结果与从商用仪器获得的图像进行比较。
