Nakajima Tsuneo, Sakai Toshihiro, Hara Hitoshi
Department of Neurology, Suita Municipal Hospital.
Rinsho Shinkeigaku. 2018 Mar 28;58(3):171-177. doi: 10.5692/clinicalneurol.cn-001107.
We report a forty-six-year-old man with a past history of brain abscess managed by surgical drainage and recurrent ischemic strokes. After treatment of brain abscess, he had been on medication for symptomatic epilepsy, but had ceased medication by his judgment. He was taken to a hospital in an ambulance for an epileptic seizure. In the hospital he suffered from drug-induced renal dysfunction caused by the intravenous anti-epileptic drug, and right hemiparesis due to ischemic stroke occurred on the third hospitalization day. He was transferred to our hospital to get a treatment for renal failure. His renal function improved gradually by hemodialysis, but an ischemic stroke recurred in the right cerebellar hemisphere. Closer examinations on the mechanisms of his strokes revealed the draining of right superior vena cava (RSVC) directly into the left atrium (LA), persistent left superior vena cava (PLSVC) and atrial septal defect (ASD). He had a rare anomaly of the systemic venous return. It seemed that his repeated strokes were caused by paradoxical embolism through the draining of RSVC to LA, and air or thrombi in the infusion lines other than intravenous thrombi was thought to be an embolic cause in this case.
我们报告了一名46岁男性,既往有脑脓肿病史,曾接受手术引流治疗,且反复发生缺血性中风。脑脓肿治疗后,他一直在服用治疗症状性癫痫的药物,但自行停药。他因癫痫发作被救护车送往医院。在医院里,他因静脉注射抗癫痫药物导致药物性肾功能不全,且在第三次住院日因缺血性中风出现右侧偏瘫。他被转至我院接受肾衰竭治疗。通过血液透析,他的肾功能逐渐改善,但右侧小脑半球再次发生缺血性中风。对其中风机制的进一步检查发现,右上腔静脉(RSVC)直接引流至左心房(LA)、永存左上腔静脉(PLSVC)和房间隔缺损(ASD)。他存在一种罕见的体静脉回流异常。他反复中风似乎是由于RSVC引流至LA导致的反常栓塞引起的,在这种情况下,除静脉血栓外,输液管路中的空气或血栓被认为是栓塞原因。