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在发展中国家巴基斯坦,I型糖尿病患者中抑郁症的发病率

Frequency of depression among patients with Type-I diabetes in a developing country, Pakistan.

作者信息

Riaz Musarrat, Imran Nazish, Fawwad Asher, Basit Abdul

机构信息

Musarrat Riaz, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi, Pakistan.

Nazish Imran, Department of Child and Family, King Edward Medical University, Lahore, Pakistan.

出版信息

Pak J Med Sci. 2017 Nov-Dec;33(6):1318-1323. doi: 10.12669/pjms.336.13911.

Abstract

OBJECTIVE

To determine the frequency of depressive symptoms among young people with Type-I diabetes.

METHODS

This cross sectional study was conducted at Baqai Institute of Diabetology & Endocrinology, Karachi, Pakistan from February to December 2015. All People aged between 12-20 years with Type-I diabetes for at least 1 year attending the OPD were included in the study. Information about participants' demographic characteristics, co morbidities and Complications, current treatment and medications were obtained. Acylated hemoglobin (HbA1C) levels were checked in all People. The Center for Epidemiologic Studies Depression (CES-D) scale was used to assess the depressive symptoms in the study participants. A cut off value of ≥ 16 was used to screen for depression. SPSS 19 was used to analyze the results.

RESULTS

Out of 104 people with Type-I diabetes, depressive symptoms were observed in 44 (42.3%) participants. Depressive symptoms were more frequent in females (28/55, 50.9%). Depressed people had more episodes of DKA (11/44, 25%), hypoglycemia (12/44, 27.3%) or hospitalization (7/44, 15.9%) in the last six months which were not statistically significant.

CONCLUSION

Depressive symptoms are quite common in people with Type-I diabetes. Health care professionals should consider screening youth with diabetes for depression regularly. Further large scale studies are needed to validate our findings.

摘要

目的

确定1型糖尿病青少年中抑郁症状的发生率。

方法

本横断面研究于2015年2月至12月在巴基斯坦卡拉奇的巴凯糖尿病与内分泌研究所进行。所有年龄在12 - 20岁、患有1型糖尿病至少1年且前来门诊就诊的患者均纳入研究。获取了参与者的人口统计学特征、合并症和并发症、当前治疗及用药信息。对所有患者进行糖化血红蛋白(HbA1C)水平检测。采用流行病学研究中心抑郁量表(CES - D)评估研究参与者的抑郁症状。使用≥16的临界值来筛查抑郁症。采用SPSS 19对结果进行分析。

结果

在104例1型糖尿病患者中,44例(42.3%)参与者存在抑郁症状。女性抑郁症状更为常见(28/55,50.9%)。在过去六个月中,抑郁患者发生糖尿病酮症酸中毒(DKA)(11/44,25%)、低血糖(12/44,27.3%)或住院(7/44,15.9%)的次数更多,但差异无统计学意义。

结论

抑郁症状在1型糖尿病患者中相当常见。医护人员应定期考虑对糖尿病青少年进行抑郁症筛查。需要进一步开展大规模研究来验证我们的研究结果。

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