秘鲁肿瘤研究所细针毛细管细胞学在可触及肿瘤中的诊断有效性。

Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru.

作者信息

Abad-Licham Milagros, Galvez-Olortegui Jose, Astigueta Juan, Díaz-Plasencia Juan

机构信息

Graduate School, Antenor Orrego Private University, Trujillo 13007, Peru.

Pathology Department, Regional Institute of Neoplastic Diseases, Trujillo 13601, Peru.

出版信息

Ecancermedicalscience. 2018 Feb 1;12:805. doi: 10.3332/ecancer.2018.805. eCollection 2018.

DOI:10.3332/ecancer.2018.805

PMID:29492099

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5828675/

Abstract

OBJECTIVE

To evaluate the diagnostic validity of fine-needle capillary cytology (FNCC) in palpable tumours.

MATERIAL AND METHODS

A retrospective, single-tray, cross-sectional diagnostic test study was carried out. We reviewed the cytological reports of the case files of the Cytology Unit of the Northern Regional Institute of Neoplastic Diseases (IREN) from January 2012 to December 2016.

RESULTS

A total of 332 patients were selected, with an average age of 54.77 years (range 13-90 years); 61.4% of patients were female. The most frequent anatomical sites were lymph nodes (49.7%), thyroid (13.3%), breast (12.3%) and soft tissues (11.4%). Twenty-five cytologies did not have a histological correlation and six showed an atypical result. In the lymph node study, the most frequent pathology was metastatic carcinoma (49.7%), followed by lymphoma (13.3%). The FNCC had a sensitivity of 99.55%, a specificity of 98.77%, a positive predictive value of 99.55% and a negative predictive value of 98.77%. The positive likelihood ratio was 80.63%.

CONCLUSIONS

FNCC is a useful, safe, reliable and economical ambulatory technique with minimal complications and high diagnostic accuracy.

摘要

目的

评估细针毛细血管细胞学检查（FNCC）在可触及肿瘤中的诊断有效性。

材料与方法

开展一项回顾性、单队列、横断面诊断试验研究。我们查阅了北部肿瘤疾病研究所（IREN）细胞学室2012年1月至2016年12月病例档案的细胞学报告。

结果

共选取332例患者，平均年龄54.77岁（范围13 - 90岁）；61.4%为女性。最常见的解剖部位是淋巴结（49.7%）、甲状腺（13.3%）、乳腺（12.3%）和软组织（11.4%）。25份细胞学检查结果与组织学无相关性，6份显示非典型结果。在淋巴结研究中，最常见的病理类型是转移性癌（49.7%），其次是淋巴瘤（13.3%）。FNCC的敏感性为99.55%，特异性为98.77%，阳性预测值为99.55%，阴性预测值为98.77%。阳性似然比为80.63%。