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靶向温度管理以改善预后:我们做到了吗?

Targeted Temperature Management for Improved Outcomes: Are We There Yet?

作者信息

Carwell Micaela

机构信息

Penn Presbyterian Medical Center, University of Pennsylvania School of Nursing, University of Pennsylvania Health System, Philadelphia.

出版信息

Crit Care Nurs Q. 2018 Apr/Jun;41(2):102-108. doi: 10.1097/CNQ.0000000000000199.

DOI:10.1097/CNQ.0000000000000199
PMID:29494366
Abstract

Therapeutic hypothermia, also referred to as targeted temperature management, has been a component of the postcardiac arrest treatment guidelines since 2010. Although almost a decade has passed since its inclusion in the postarrest guidelines, many unanswered questions remain regarding selection of the appropriate patient population, optimal target temperature, ideal window of time in which to initiate therapy after arrest, most efficient, safe, and accurate equipment choice for inducing and maintaining hypothermia, most effective duration of treatment, and rate of cooling or rewarming. On a national and international level, critical care nurses are in a unique position to participate in research that will define targeted temperature management protocols and practices. Nurses are also ideal for standardizing the targeted temperature management policy and protocol locally and nationally based on current available evidence. This review aims to serve 2 purposes: first, to provide a broad update on the current clarifications and limitations per research findings on target temperature management therapy; second, to explain how critical care nurses can use this updated information to improve outcomes for their patients with cardiac arrest.

摘要

治疗性低温,也称为目标温度管理,自2010年以来一直是心脏骤停后治疗指南的一部分。尽管自其被纳入骤停后指南以来已过去近十年,但关于合适患者群体的选择、最佳目标温度、骤停后开始治疗的理想时间窗、诱导和维持低温最有效、安全且准确的设备选择、最有效的治疗持续时间以及降温或复温速率等问题仍有许多未得到解答。在国家和国际层面,重症护理护士处于独特地位,能够参与确定目标温度管理方案和实践的研究。护士也是根据现有证据在本地和全国范围内规范目标温度管理政策和方案的理想人选。本综述旨在实现两个目的:第一,根据目标温度管理治疗的研究结果,对当前的澄清内容和局限性进行广泛更新;第二,解释重症护理护士如何利用这些更新信息改善心脏骤停患者的治疗效果。

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Targeted Temperature Management for Improved Outcomes: Are We There Yet?靶向温度管理以改善预后:我们做到了吗?
Crit Care Nurs Q. 2018 Apr/Jun;41(2):102-108. doi: 10.1097/CNQ.0000000000000199.
2
Temperature Management After Cardiac Arrest: An Advisory Statement by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation and the American Heart Association Emergency Cardiovascular Care Committee and the Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation.心脏骤停后的体温管理:复苏国际联络委员会高级生命支持工作组、美国心脏协会急救心血管护理委员会以及心肺、危重病、围术期和复苏理事会的咨询声明。
Resuscitation. 2016 Jan;98:97-104. doi: 10.1016/j.resuscitation.2015.09.396. Epub 2015 Oct 9.
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Effectiveness of Two Targeted Temperature Management Methods After Pediatric Postcardiac Arrest: A Multicenter International Study.两种儿科心搏骤停后目标温度管理方法的有效性:一项多中心国际研究。
Pediatr Crit Care Med. 2019 Feb;20(2):e77-e82. doi: 10.1097/PCC.0000000000001813.
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How Cool It Is: Targeted Temperature Management for Brain Protection Post-Cardiac Arrest.多么酷啊:心脏骤停后脑保护的目标温度管理。
Semin Respir Crit Care Med. 2016 Feb;37(1):34-41. doi: 10.1055/s-0035-1570357. Epub 2016 Jan 28.
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Do Lower Target Temperatures or Prolonged Cooling Provide Improved Outcomes for Comatose Survivors of Cardiac Arrest Treated With Hypothermia?较低的目标温度或延长降温时间能否改善接受低温治疗的心脏骤停昏迷幸存者的预后?
J Am Heart Assoc. 2015 Sep 21;4(9):e002123. doi: 10.1161/JAHA.115.002123.
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Therapeutic hypothermia following cardiac arrest.心脏骤停后的治疗性低温。
Best Pract Res Clin Anaesthesiol. 2013 Sep;27(3):335-46. doi: 10.1016/j.bpa.2013.07.003.
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Pathway for the management of survivors of out-of-hospital cardiac arrest.院外心脏骤停幸存者的管理路径
Crit Pathw Cardiol. 2010 Jun;9(2):49-54. doi: 10.1097/HPC.0b013e3181dc4d14.
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[Therapeutic hypothermia in 2015 : Influence of the TTM study on the intensive care procedure after cardiac arrest].2015年的治疗性低温:目标温度管理(TTM)研究对心脏骤停后重症监护程序的影响
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Therapeutic hypothermia following resuscitation.复苏后的治疗性低温
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Is hypothermia indicated during cardiopulmonary resuscitation and after restoration of spontaneous circulation?
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2
Increasing the Effectiveness of Targeted Temperature Management.提高目标温度管理的效果。
Crit Care Nurse. 2021 Oct 1;41(5):59-63. doi: 10.4037/ccn2021637.