Zhao D, Ma X L, Wang W L, Zhang L
Orthopaedic Department, General Hospital of Tianjin Medical University, Tianjin 300052, China.
Zhonghua Yi Xue Za Zhi. 2018 Feb 13;98(7):519-523. doi: 10.3760/cma.j.issn.0376-2491.2018.07.007.
To investigate the clinical effect of enhanced recovery after surgery (ERAS) in unilateral total knee arthroplasty (TKA). Retrospective analysis of 98 patients received unilateral TKA from September 2015 to September 2016 in the Orthopaedic Departmentof Affiliated Hospital of Logistics University of Chinese People's Armed Police Forces.Of the patients, 52 cases were treated by traditional operation (routine group) and the other 46 cases were treated with ERAS concept (ERAS group). The following data were gathered and statistically analyzed between the groups: gender, age, body mass index, preoperative hemoglobin, preoperative visual analogue scale (VAS) score, postoperative visible blood loss, postoperative hemoglobin at 24 hour after operation, blood transfusion rate, postoperative VAS score, length of hospital stay, the satisfaction rate, preoperative and 1 and 6 months postoperative evaluation with hospital for special surgery knee score (HSS), postoperative range of motion (ROM) of knees after 2 weeks, 1 month and 6 months of surgery, incidence rate of complications after surgery.Data between groups were analyzed with one-factor analysis of variance or chi-square test. There was no significant difference in preoperative data between two groups.Postoperative visible blood loss of ERAS group was significantly lower than that in routine group[(224±59) vs (361±70) ml, =4.723, <0.01]; postoperative hemoglobin after 24 hours in ERAS group was significantly higher than that in routine group[(109±8) vs (96±10) g/L, =-3.297, =0.004]; blood transfusion rate of ERAS group was significantly lower than that in routine group[6.5 %(3/46) vs 46.2%(24/52), χ(2)=19.207, <0.01]; the 12-hour and 48-hour postoperative VAS scores in ERAS groups were both significantly lower than those in routine group (=3.708, 3.894, both <0.05); length of hospital stay in ERAS group was significantly shorter than that in routine group[(6.8±1.2) vs (13.1±2.6) d, =6.924, <0.01]; HSS scores of ERAS groups at 1 month and 6 months after surgery were both significantly higher than those in routine group (=-3.677, -3.594, both <0.05); knees ROM in ERAS group at 2 weeks and 1 month after surgery were both significantly higher than those in routine group (=-4.628, -4.442, both <0.05); the rate of postoperative nausea vomiting in ERAS group was significantly lower than that in routine group[13.0%(6/46) vs 48.1%(25/52), χ(2)=13.852, =0.002]. VAS score at 1 month after surgery, knees ROM at 6 months after surgery and the satisfaction rate were all comparable between the two groups (=0.412, -1.026, χ(2)=3.695, all >0.05). Condition of patients treated by unilateral TKA under ERAS model improves effectively during perioperative period when compared with routine treatment, patients have earlier rehabilitation and better experience in hospital and operation.
探讨加速康复外科(ERAS)在单侧全膝关节置换术(TKA)中的临床效果。回顾性分析2015年9月至2016年9月在中国人民武装警察部队后勤学院附属医院骨科接受单侧TKA的98例患者。其中,52例采用传统手术治疗(常规组),另外46例采用ERAS理念治疗(ERAS组)。收集两组患者的以下数据并进行统计学分析:性别、年龄、体重指数、术前血红蛋白、术前视觉模拟评分(VAS)、术后可见失血量、术后24小时血红蛋白、输血率、术后VAS评分、住院时间、满意率、术前及术后1个月和6个月采用医院特殊外科膝关节评分(HSS)进行评估、术后2周、1个月和6个月膝关节活动度(ROM)、术后并发症发生率。组间数据采用单因素方差分析或卡方检验。两组术前数据无显著差异。ERAS组术后可见失血量明显低于常规组[(224±59) vs (361±70)ml,t = 4.723,P < 0.01];ERAS组术后24小时血红蛋白明显高于常规组[(109±8) vs (96±10)g/L,t = -3.297,P = 0.004];ERAS组输血率明显低于常规组[6.5%(3/46) vs 46.2%(24/52),χ² = 19.207,P < 0.01];ERAS组术后12小时和48小时VAS评分均明显低于常规组(t = 3.708,3.894,均P < 0.05);ERAS组住院时间明显短于常规组[(6.8±1.2) vs (13.1±2.6)d,t = 6.924,P < 0.01];ERAS组术后1个月和6个月HSS评分均明显高于常规组(t = -3.677,-3.594,均P < 0.05);ERAS组术后2周和1个月膝关节ROM均明显高于常规组(t = -4.628,-4.442,均P < 0.05);ERAS组术后恶心呕吐发生率明显低于常规组[13.0%(6/46) vs 48.1%(25/52),χ² = 13.852,P = 0.002]。两组术后1个月VAS评分、术后6个月膝关节ROM及满意率均无差异(t = 0.412,-1.026,χ² = 3.695,均P > 0.05)。与常规治疗相比,ERAS模式下单侧TKA患者围手术期情况有效改善,患者康复更早,住院及手术体验更佳。