5-脂氧合酶抑制的抗炎作用 - Suppr | 超能文献

Antiinflammatory consequences of 5-lipoxygenase inhibition.

作者信息

Ackerman N R, Arner E C, Galbraith W, Harris R R, Jaffee B D, Mackin W M

出版信息

Adv Prostaglandin Thromboxane Leukot Res. 1986;16:47-62.

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Antiinflammatory consequences of 5-lipoxygenase inhibition.5-脂氧合酶抑制的抗炎作用

Adv Prostaglandin Thromboxane Leukot Res. 1986;16:47-62.

2

Manipulations of arachidonic acid metabolism using a 5-lipoxygenase inhibitor in transfusion-induced immunosuppression.在输血诱导的免疫抑制中使用5-脂氧合酶抑制剂对花生四烯酸代谢进行调控。

Transplant Proc. 1988 Dec;20(6):1186-9.

3

Inhibitory effect of exogenous arachidonic acid on alveolar macrophage 5-lipoxygenase metabolism. Role of ATP depletion.外源性花生四烯酸对肺泡巨噬细胞5-脂氧合酶代谢的抑制作用。ATP耗竭的作用。

J Immunol. 1988 Mar 15;140(6):1958-66.

4

L-652,343: a novel dual 5-lipoxygenase/cyclooxygenase inhibitor.L-652,343：一种新型的5-脂氧合酶/环氧化酶双重抑制剂。

Adv Prostaglandin Thromboxane Leukot Res. 1986;16:63-6.

5

Pharmacology of the dual inhibitor of cyclooxygenase and 5-lipoxygenase 3-hydroxy-5-trifluoromethyl-N-(2-(2-thienyl)-2-phenyl-ethenyl)-benzo (b)thiophene-2-carboxamide.

Arzneimittelforschung. 1988 Mar;38(3):372-8.

6

The antiinflammatory action of guanabenz is mediated through 5-lipoxygenase and cyclooxygenase inhibition.胍那苄的抗炎作用是通过抑制5-脂氧合酶和环氧化酶介导的。

Eur J Pharmacol. 1987 Oct 13;142(2):197-205. doi: 10.1016/0014-2999(87)90108-7.

7

New cyclooxygenase-2/5-lipoxygenase inhibitors. 1. 7-tert-buty1-2,3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: discovery and variation of the 5-keto substituent.新型环氧化酶-2/5-脂氧合酶抑制剂。1. 7-叔丁基-2,3-二氢-3,3-二甲基苯并呋喃衍生物作为胃肠道安全的抗炎和镇痛剂：5-酮取代基的发现与变化

J Med Chem. 1998 Mar 26;41(7):1112-23. doi: 10.1021/jm970679q.

8

Role of 5-lipoxygenase (5-LO) metabolites in ACTH-stimulated steroidogenesis.

Adv Prostaglandin Thromboxane Leukot Res. 1987;17B:704-7.

9

2-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity.2-取代-1-萘酚作为具有局部抗炎活性的强效5-脂氧合酶抑制剂。

J Med Chem. 1990 Jan;33(1):360-70. doi: 10.1021/jm00163a058.

10

New cyclooxygenase-2/5-lipoxygenase inhibitors. 2. 7-tert-butyl-2,3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: variations of the dihydrobenzofuran ring.新型环氧化酶-2/5-脂氧合酶抑制剂。2. 作为胃肠道安全性抗炎和镇痛药的7-叔丁基-2,3-二氢-3,3-二甲基苯并呋喃衍生物：二氢苯并呋喃环的变体

J Med Chem. 1998 Mar 26;41(7):1124-37. doi: 10.1021/jm970680p.

引用本文的文献

1

Comparative evaluation of arachidonic acid (AA)- and tetradecanoylphorbol acetate (TPA)-induced dermal inflammation.

Inflammation. 1993 Dec;17(6):723-41. doi: 10.1007/BF00920477.

2

Orally administered tolfenamic acid inhibits leukotriene synthesis in isolated human peripheral polymorphonuclear leukocytes.口服托芬那酸可抑制离体人外周多形核白细胞中白三烯的合成。

Agents Actions. 1989 Aug;28(1-2):83-8. doi: 10.1007/BF02022985.

3

Modulation of arachidonic acid metabolism by orally administered morniflumate in man.口服莫尼氟酯对人体花生四烯酸代谢的调节作用。

Agents Actions. 1991 Jul;33(3-4):233-9. doi: 10.1007/BF01986568.