Measurement of normal fetal cerebellar vermis at 24-32 weeks of gestation by transabdominal ultrasound and magnetic resonance imaging: A prospective comparative study.

OBJECTIVES

Fetal cerebellar vermis may be assessed by ultrasound (US) or magnetic resonance imaging (MRI), and median-plane views are best for evaluation. The purpose of this study was to compare measurements of normal fetal vermis at 24-32 weeks of gestation obtained in median plane by transabdominal 2D-US, 3D-US, and MRI.

METHODS

A prospective study was conducted, examining normal singleton fetuses between 24 and 32 weeks of gestation. Within a 24-h period, median-plane views of posterior fossa were generated using 2D-US, 3D-US, and MRI. Measurements of anteroposterior (AP) diameter, craniocaudal (CC) diameter, mid-sagittal surface area, brainstem-vermis (BV) angle and brainstem-tentorium (BT) angle were obtained to compare these imaging modalities.

RESULTS

A total of 180 fetuses were studied. Correlation among imaging methods was good, marked by the following intraclass correlation coefficients: AP diameter, 0.955; CC diameter, 0.956; mid-sagittal surface area, 0.982; BV angle, 0.810; and BT angle, 0.865 (p < 0.001).

CONCLUSIONS

Visualization rates of MRI, 3D-US, and transabdominal 2D-US were decremental, MRI being superior in this regard. However, these three imaging modalities correlated well in measuring cerebellar vermis and its surroundings.