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琥珀酰胆碱与罗库溴铵作为假性胆碱酯酶缺乏患者电休克治疗神经肌肉阻滞剂的比较。

Comparison between succinylcholine and rocuronium as neuromuscular blocking agents for electroconvulsive therapy in a patient with pseudocholinesterase deficiency.

作者信息

Takazawa Tomonori, Suto Takashi, Aihara Masako, Anzai Takeshi, Horiuchi Tatsuo, Yamada Makiko H, Kadoi Yuji, Saito Shigeru

机构信息

Department of Anesthesiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, 371-8511 Japan.

Department of Psychiatry, Gunma Prefectural Psychiatric Medical Center, 2-2374 Kunisada-machi, Isesaki, 379-2221 Japan.

出版信息

JA Clin Rep. 2015;1(1):7. doi: 10.1186/s40981-015-0009-2. Epub 2015 Aug 27.

DOI:10.1186/s40981-015-0009-2
PMID:29497639
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5818691/
Abstract

We report here the anesthetic management of a patient with schizophrenia and pseudocholinesterase deficiency. Electroconvulsive therapy was performed using succinylcholine and rocuronium as the neuromuscular blocking agents in the first seven and latter six treatments, respectively. The recovery time from muscle relaxation after succinylcholine administration was remarkably longer than that after rocuronium-sugammadex administration. Rocuronium and sugammadex appear to be useful in situations in which succinylcholine is contraindicated.

摘要

我们在此报告一名患有精神分裂症和假性胆碱酯酶缺乏症患者的麻醉管理情况。在前七次治疗中分别使用琥珀酰胆碱和罗库溴铵作为神经肌肉阻滞剂进行电休克治疗,在后六次治疗中分别使用罗库溴铵和舒更葡糖进行电休克治疗。琥珀酰胆碱给药后肌肉松弛的恢复时间明显长于罗库溴铵 - 舒更葡糖给药后的恢复时间。在琥珀酰胆碱禁忌的情况下,罗库溴铵和舒更葡糖似乎是有用的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bb/5818691/48126ada1af3/40981_2015_9_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bb/5818691/48126ada1af3/40981_2015_9_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bb/5818691/48126ada1af3/40981_2015_9_Fig1_HTML.jpg

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本文引用的文献

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Three suspected cases of sugammadex-induced anaphylactic shock.三例疑似舒更葡糖钠所致过敏性休克病例。
BMC Anesthesiol. 2014 Oct 17;14:92. doi: 10.1186/1471-2253-14-92. eCollection 2014.
2
Hypersensitivity associated with sugammadex administration: a systematic review.与 sugammadex 给药相关的过敏反应:系统评价。
Anaesthesia. 2014 Nov;69(11):1251-7. doi: 10.1111/anae.12736. Epub 2014 May 22.
3
Recovery time after sugammadex reversal of rocuronium-induced muscle relaxation for electroconvulsive therapy is independent of cardiac output in both young and elderly patients.
在接受电休克治疗的患者中,使用 sugammadex 逆转罗库溴铵诱导的肌肉松弛后,恢复时间与心输出量无关,无论患者年龄大小。
J ECT. 2013 Mar;29(1):33-6. doi: 10.1097/YCT.0b013e31826cf348.
4
Hypersensitivity reactions during anesthesia. Results from the ninth French survey (2005-2007).麻醉期间的过敏反应。第九次法国调查(2005-2007 年)的结果。
Minerva Anestesiol. 2012 Aug;78(8):868-78. Epub 2012 Mar 22.
5
Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy.比较三种不同剂量琥珀酸舒更葡糖钠和琥珀酰胆碱用于电抽搐治疗时罗库溴铵诱导的肌肉松弛逆转后恢复时间。
J Anesth. 2011 Dec;25(6):855-9. doi: 10.1007/s00540-011-1236-y. Epub 2011 Sep 24.
6
Use of rocuronium-sugammadex, an alternative to succinylcholine, as a muscle relaxant during electroconvulsive therapy.在电抽搐治疗中使用罗库溴铵-琥珀胆碱作为肌肉松弛剂的替代药物。
J Anesth. 2011 Apr;25(2):286-90. doi: 10.1007/s00540-011-1095-6. Epub 2011 Feb 4.
7
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J ECT. 2011 Mar;27(1):e47-8. doi: 10.1097/YCT.0b013e318205e1d3.
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Anesthesiology. 2009 May;110(5):1020-5. doi: 10.1097/ALN.0b013e31819dabb0.