Jagannadha Rao A, Moudal N R, Li C H
Int J Pept Protein Res. 1986 Nov;28(5):546-8. doi: 10.1111/j.1399-3011.1986.tb03291.x.
Human beta-endorphin has been administered by nasal spray technique at a dose of 0.02 mg per kg in female bonnet monkeys. A significant increase of serum prolactin levels was observed within 30 min and maintained up to 60 min. In the same dose, intravenous injections of the hormone caused a marginal increase of prolactin levels only after 60 min. It was concluded that administration of beta-endorphin by nasal spray is more effective than the intravenous injection.
已采用鼻腔喷雾技术，以每千克0.02毫克的剂量给雌性冠毛猕猴注射人β-内啡肽。在30分钟内观察到血清催乳素水平显著升高，并持续至60分钟。以相同剂量静脉注射该激素，仅在60分钟后催乳素水平才有少量升高。得出的结论是，通过鼻腔喷雾给予β-内啡肽比静脉注射更有效。
