老年患者头颈部癌症的管理

Management of head and neck cancer in older patients.

作者信息

Magnano Mauro, Bertone Fabio, Andreis Marco, Boffano Paolo, Machetta Giacomo

机构信息

Division of Otolaryngology, Pinerolo and Rivoli Hospitals, ASL TO3, Pinerolo, Italy.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Apr;125(4):369-375. doi: 10.1016/j.oooo.2018.01.022. Epub 2018 Feb 1.

DOI:10.1016/j.oooo.2018.01.022

PMID:29501356

Abstract

OBJECTIVE

A progressive increase in the number of older patients with head and neck cancer has been observed in the last few years. The aim of this study was to assess our experience in the management of older patients with head and neck cancer (HNC) in comparison with younger patients.

STUDY DESIGN

A retrospective review was conducted for all patients admitted and treated for newly diagnosed HNC between January 2008 and December 2012. The clinical characteristics, management approaches, and outcome data were recorded.

RESULTS

In total, 316 patients with HNC (232 males, 84 females) were enrolled: 203 (64%) were in the young group, whereas 113 patients (36%) were in the older group. Comorbidities (P < .000005) and stage IV tumors (P < .0005) were more frequently observed in the older group. Treatment options were uniformly distributed within the 2 groups; only radiotherapy alone was more frequently administered in older patients (P < .0005).

CONCLUSIONS

Chronologic age should not be a reason to deny appropriate treatments that could prevent death in older patients. A careful pretreatment assessment should always be performed.

摘要