Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, Bari, Italy; National Cancer Institute "Giovanni Paolo II", Bari, Italy.
Microvasc Res. 2018 Jul;118:57-60. doi: 10.1016/j.mvr.2018.02.008. Epub 2018 Mar 5.
Arteriogenesis is defined as the growth of functional collateral arteries from pre-existing arterio-arteriolar anastomoses. The role of mast cells in arteriogenesis is largely unexplored. Recent evidences suggest that mast cells together with other inflammatory cells, including monocytes-macrophages, lymphocytes, NK cells and endothelial precursor cells (EPCs) may be involved in this process. This review article analyzes the literature concerning this new aspect of biological activity of mast cells.
动脉生成是指从预先存在的动静脉吻合支生长出功能性侧支动脉。肥大细胞在动脉生成中的作用在很大程度上尚未被探索。最近的证据表明，肥大细胞与其他炎症细胞（包括单核细胞-巨噬细胞、淋巴细胞、NK 细胞和内皮祖细胞（EPC））一起可能参与这个过程。本文分析了关于肥大细胞这种新的生物学活性的文献。
