Yang Huiliang, Im Gi Hye, Nielsen Gunnlaugur Petur, Kheterpal Arvin, Schwab Joseph H
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, People's Republic of China.
Department of Orthopaedic Surgery, Orthopaedic Spine and Oncology Services, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Skeletal Radiol. 2018 Oct;47(10):1431-1435. doi: 10.1007/s00256-018-2911-y. Epub 2018 Mar 3.
Spinal giant cell tumor of bone (GCTB) is a rare benign, but locally aggressive, entity. We report the case of a 40-year-old man diagnosed with GCTB of the thoracic spine. The only symptom upon presentation was progressive back pain with pain radiating to the chest. Magnetic resonance imaging showed that the soft tissue mass extended posteriorly into the spinal canal, causing severe spinal cord compression. We initially treated this case with Decadron (Fresenius kabi, Bad Homburg vor der Hohe, Germany) for 1 week. This led to a reduction of tumor size and decompression of the spinal cord. To the best of our knowledge, there have been no prior reports of primary GCTB sensitive to steroid therapy within the existing literature.
脊柱骨巨细胞瘤(GCTB)是一种罕见的良性但具有局部侵袭性的疾病。我们报告一例40岁男性被诊断为胸椎GCTB的病例。就诊时唯一的症状是进行性背痛并向胸部放射。磁共振成像显示软组织肿块向后延伸至椎管,导致严重的脊髓压迫。我们最初用德卡德龙(德国费森尤斯卡比公司,巴特洪堡)对该病例进行了1周的治疗。这导致肿瘤体积缩小和脊髓减压。据我们所知,现有文献中尚无原发性GCTB对类固醇治疗敏感的先前报道。