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单次注射透明质酸钠治疗肱骨外上髁炎的疗效

Efficacy Of A Single-Injection Sodium Hyaluronate Treatment In Lateral Epicondylitis.

作者信息

Khan Inam Ullah, Awan Abdus Saboor, Khan Aimal Sattar, Marwat Imran, Meraj Muhammad

机构信息

Department of Orthopaedics,Khyber Medical College, Peshawar-Pakistan.

Department of Orthopaedics, Lady Reading Hospital, Peshawar, Pakistan.

出版信息

J Ayub Med Coll Abbottabad. 2018 Jan-Mar;30(1):85-89.

Abstract

BACKGROUND

Lateral epicondylitis or tennis elbow is a disease of tendons arising from common extensor origin at the lateral epicondyle of elbow and is commonly characterized by pain on supination of forearms as well as extension of fingers and wrists.

METHODS

This descriptive case series aims to determine the efficacy of a single-injection sodium hyaluronate treatment for lateral epicondylitis. The study was conducted at the Department of Orthopaedics. Ayub Teaching Hospital Abbottabad. From February 1 to August 31, 2014. Patients diagnosed with lateral epicondylitis were administered 1 cc of 1% Sodium hyaluronate 1 cm from the lateral epicondyle into the soft tissue.

RESULTS

Hyaluronic acid is more effective in patients with moderate pain of lateral epicondylitis (VAS score ≤7 than in patients with severe pain (VAS score >7). Paired sample t-test was used to compared the means of the pre- and post-procedure VAS score and the difference was found to be statistically very significant (p=0.00) with a mean±SD change in VAS of 2.31±1.35 at 4 weeks.

CONCLUSIONS

A single injection of sodium hyaluronate is effective in management of moderate, but not severe pain of lateral epicondylitis.

摘要

背景

外侧上髁炎或网球肘是一种起源于肘部外侧上髁常见伸肌起点的肌腱疾病,其常见特征是前臂旋后以及手指和手腕伸展时疼痛。

方法

本描述性病例系列旨在确定单次注射透明质酸钠治疗外侧上髁炎的疗效。该研究在阿伯塔巴德阿尤布教学医院骨科进行。时间为2014年2月1日至8月31日。诊断为外侧上髁炎的患者在距外侧上髁1厘米处的软组织内注射1毫升1%的透明质酸钠。

结果

透明质酸对外侧上髁炎中度疼痛患者(视觉模拟评分法[VAS]评分≤7)比重度疼痛患者(VAS评分>7)更有效。采用配对样本t检验比较治疗前后VAS评分的均值,发现差异具有统计学意义(p = 0.00),4周时VAS的平均变化±标准差为2.31±1.35。

结论

单次注射透明质酸钠对治疗外侧上髁炎的中度疼痛有效,但对重度疼痛无效。

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