1 Department of Physical Education, Sao Paulo State University, Bauru, Brazil.
2 Department of Medical Clinic, Sao Paulo State University, Botucatu, Brazil.
Clin Rehabil. 2018 Jul;32(7):899-908. doi: 10.1177/0269215518760696. Epub 2018 Mar 4.
This study aimed to investigate the effect of continuous progressive resistance training on body composition, functional capacity and self-reported quality of life in end-stage renal disease patients.
A randomized controlled trial.
The study included 52 hemodialysis patients (aged 55.7 ± 14.03 years) randomized into exercise (progressive resistance training (PRT), n = 28) or control (CON, n = 24) groups.
Patients randomized into the PRT group received prescribed strength exercises in two sets of 15-20 repetitions, in a repetition maximum training zone regime, thrice a week for 12 weeks, during hemodialysis. Patients randomized into the CON group received a sham-exercise with active mobilization of the arms and legs without load and progression.
Body composition using dual-energy X-ray absorptiometry (DXA), strength using handgrip dynamometry (HGS), repeated sit-to-stand test (STT), 6-minute walk test, flexibility and the SF-36 questionnaire (quality of life (QoL)) were assessed at baseline and at 12 weeks.
Leg lean mass ( P = 0.04, effect size (ES) of 0.56), bone mineral content ( P = 0.02, ES of 0.65), leg strength in STT repetitions ( P = 0.01, ES of 0.66) and flexibility ( P < 0.01, ES of 1.03) were significantly improved in the PRT group compared to the CON group. Walking capacity, HGS and QoL were not different between the groups.
12 weeks of PRT with a repetition maximum training zone regime provided significant load to increase leg lean mass and STT performance as well as bone mineral content, compared to the CON, which continued to deteriorate. There was lack of efficacy on walking test, HGS and QoL.
本研究旨在探讨连续渐进性抗阻训练对终末期肾病患者身体成分、功能能力和自我报告生活质量的影响。
随机对照试验。
本研究纳入了 52 名血液透析患者（年龄 55.7±14.03 岁），随机分为运动组（渐进性抗阻训练（PRT），n=28）或对照组（CON，n=24）。
随机进入 PRT 组的患者在血液透析期间每周三次接受两组 15-20 次重复、最大重复训练区方案的规定力量练习，持续 12 周。随机进入 CON 组的患者接受假运动，即手臂和腿部主动活动但无负荷和进展。
使用双能 X 射线吸收法（DXA）评估身体成分、使用握力计（HGS）评估力量、重复坐立测试（STT）、6 分钟步行测试、柔韧性和 SF-36 问卷（生活质量（QoL）），在基线和 12 周时进行评估。
与 CON 组相比，PRT 组的腿部瘦体重（P=0.04，效应大小（ES）为 0.56）、骨矿物质含量（P=0.02，ES 为 0.65）、STT 重复次数的腿部力量（P=0.01，ES 为 0.66）和柔韧性（P<0.01，ES 为 1.03）均显著改善。步行能力、HGS 和 QoL 两组之间无差异。
与 CON 相比，12 周的 PRT 采用最大重复训练区方案提供了显著的负荷，可以增加腿部瘦体重和 STT 表现以及骨矿物质含量，而 CON 则继续恶化。对步行测试、HGS 和 QoL 没有疗效。
