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[一名接受英夫利昔单抗治疗的肛周克罗恩病患者并发急性阑尾炎]

[Acute appendicitis in a patient with perianal Crohn's disease receiving infliximab].

作者信息

Szakács Zsolt, Faluhelyi Nándor, Fincsur András, Papp András, Vincze Áron, Bajor Judit

机构信息

Transzlációs Medicina Intézet, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs, Szigeti út 12., 7624.

Klinikai Központ, Radiológiai Klinika, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs.

出版信息

Orv Hetil. 2018 Mar;159(10):405-409. doi: 10.1556/650.2018.30982.

Abstract

The differential diagnosis of acute abdominal complaints is challenging in Crohn's disease. This is particularly true in patients in remission induced by biological therapy. In addition to the acute relapse of Crohn's disease, other common causes, such as acute appendicitis exhibiting similar and often atypical course, should be taken into consideration irrespective of the age. An ileocecal flare-up is unlikely to occur in patients with perianal Crohn's disease in remission induced by infliximab even if laboratory and radiological findings point towards this diagnosis. We report the case of a middle-aged woman in remission induced by infliximab who developed acute abdominal symptoms due to perforated appendicitis. Orv Hetil. 2018; 159(10): 405-409.

摘要

在克罗恩病中,急性腹部症状的鉴别诊断具有挑战性。对于接受生物治疗诱导缓解的患者而言尤其如此。除了克罗恩病的急性复发外,其他常见病因,如表现出相似且往往不典型病程的急性阑尾炎,无论患者年龄多大都应予以考虑。即使实验室和影像学检查结果指向回盲部克罗恩病发作的诊断,接受英夫利昔单抗诱导缓解的肛周克罗恩病患者也不太可能出现这种情况。我们报告了一例接受英夫利昔单抗诱导缓解的中年女性因阑尾炎穿孔出现急性腹部症状的病例。《匈牙利医学周报》。2018年;159(10): 405 - 409。

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