• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

痴呆症诊断中的循环推理。

Circular Inference in Dementia Diagnostics.

机构信息

Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.

Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

出版信息

J Alzheimers Dis. 2018;63(1):69-73. doi: 10.3233/JAD-180050.

DOI:10.3233/JAD-180050
PMID:29504544
Abstract

Referring to recent international articles stating that amyloid imaging or detection has a high additive value in making a diagnosis of Alzheimer's disease (AD) when previous investigations are inconclusive, the authors of this editorial argue that this statement is based on circular reasoning and, hence, misleading. Since autopsy findings and other potential indicators fit poorly with amyloid PET, they conclude that this examination has no role in the diagnosis of AD.

摘要

针对近期国际文章提出的,在先前的研究结果不确定的情况下,淀粉样蛋白成像或检测对阿尔茨海默病(AD)的诊断具有较高的附加价值的观点,本文编辑认为,这种说法基于循环推理,因此具有误导性。由于尸检结果和其他潜在的指标与淀粉样蛋白 PET 不匹配,他们得出结论,这种检查在 AD 的诊断中没有作用。

相似文献

1
Circular Inference in Dementia Diagnostics.痴呆症诊断中的循环推理。
J Alzheimers Dis. 2018;63(1):69-73. doi: 10.3233/JAD-180050.
2
Flutemetamol (18F): a β-amyloid positron emission tomography tracer for Alzheimer's and dementia diagnosis.氟代甲磺酸美他莫(18F):一种用于阿尔茨海默病和痴呆症诊断的β淀粉样蛋白正电子发射断层显像剂。
Drugs Today (Barc). 2014 Mar;50(3):219-29. doi: 10.1358/dot.2014.50.3.2116672.
3
[Visualization of amyloid with positron emission tomography. Useful improvement in the diagnosis of dementia?].[正电子发射断层扫描对淀粉样蛋白的可视化。对痴呆症诊断有帮助的改进?]
Nervenarzt. 2010 May;81(5):602-6. doi: 10.1007/s00115-010-2951-6.
4
Clinical Utility of Amyloid PET Imaging in the Differential Diagnosis of Atypical Dementias and Its Impact on Caregivers.淀粉样蛋白PET成像在非典型痴呆鉴别诊断中的临床应用及其对护理人员的影响。
J Alzheimers Dis. 2016 Apr 18;52(4):1251-62. doi: 10.3233/JAD-151180.
5
Additive value of amyloid-PET in routine cases of clinical dementia work-up after FDG-PET.FDG-PET 后常规临床痴呆评估病例中淀粉样蛋白-PET 的附加价值。
Eur J Nucl Med Mol Imaging. 2017 Dec;44(13):2239-2248. doi: 10.1007/s00259-017-3832-z. Epub 2017 Sep 20.
6
Radiolabeled bioactive benzoheterocycles for imaging β-amyloid plaques in Alzheimer's disease.用于阿尔茨海默病中β-淀粉样蛋白斑块成像的放射性标记生物活性苯并杂环化合物。
Eur J Med Chem. 2014 Nov 24;87:703-21. doi: 10.1016/j.ejmech.2014.10.012. Epub 2014 Oct 7.
7
Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer's disease.常染色体显性遗传性阿尔茨海默病中星形细胞增生和淀粉样蛋白PET的纵向变化差异
Brain. 2016 Mar;139(Pt 3):922-36. doi: 10.1093/brain/awv404. Epub 2016 Jan 26.
8
[(18)F]flutemetamol amyloid positron emission tomography in preclinical and symptomatic Alzheimer's disease: specific detection of advanced phases of amyloid-β pathology.[(18)F]氟替美莫淀粉样蛋白正电子发射断层扫描在临床前和有症状的阿尔茨海默病中的应用:对淀粉样β病理的先进阶段的特异性检测。
Alzheimers Dement. 2015 Aug;11(8):975-85. doi: 10.1016/j.jalz.2015.05.018. Epub 2015 Jun 30.
9
Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum.跨阿尔茨海默病谱系的β-淀粉样蛋白阶段的临床病理特征及11C-匹兹堡化合物B的意义
Brain. 2015 May;138(Pt 5):1370-81. doi: 10.1093/brain/awv050. Epub 2015 Mar 23.
10
Accumulation of amyloid in cognitive impairment after mild traumatic brain injury.轻度创伤性脑损伤后认知障碍中淀粉样蛋白的积累。
J Neurol Sci. 2015 Feb 15;349(1-2):99-104. doi: 10.1016/j.jns.2014.12.032. Epub 2014 Dec 30.

引用本文的文献

1
FDG-PET versus Amyloid-PET Imaging for Diagnosis and Response Evaluation in Alzheimer's Disease: Benefits and Pitfalls.18F-氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)与淀粉样蛋白正电子发射断层扫描(Amyloid-PET)在阿尔茨海默病诊断及疗效评估中的应用:优势与局限
Diagnostics (Basel). 2023 Jul 3;13(13):2254. doi: 10.3390/diagnostics13132254.
2
The contribution of beta-amyloid to dementia in Lewy body diseases: a 1-year follow-up study.β-淀粉样蛋白在路易体病所致痴呆中的作用:一项为期1年的随访研究。
Brain Commun. 2021 Aug 19;3(3):fcab180. doi: 10.1093/braincomms/fcab180. eCollection 2021.
3
A Cost-Consequence Analysis of Different Screening Procedures in Alzheimer's Disease: Results from the MOPEAD Project.
不同阿尔茨海默病筛查程序的成本-效益分析:来自 MOPEAD 项目的结果。
J Alzheimers Dis. 2021;83(3):1149-1159. doi: 10.3233/JAD-210303.
4
Proton Magnetic Resonance Spectroscopy in Common Dementias-Current Status and Perspectives.常见痴呆症中的质子磁共振波谱分析——现状与展望
Front Psychiatry. 2020 Aug 6;11:769. doi: 10.3389/fpsyt.2020.00769. eCollection 2020.
5
Suboptimal validity of amyloid imaging-based diagnosis and management of Alzheimer's disease: why it is time to abandon the approach.基于淀粉样蛋白成像的阿尔茨海默病诊断与管理的有效性欠佳:为何是时候摒弃这种方法了。
Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):225-230. doi: 10.1007/s00259-019-04564-5.
6
Young-onset dementia: scoping review of key pointers to diagnostic accuracy.早发性痴呆:诊断准确性关键指标的范围综述
BJPsych Open. 2019 Jun 4;5(3):e48. doi: 10.1192/bjo.2019.36.
7
An update on the unparalleled impact of FDG-PET imaging on the day-to-day practice of medicine with emphasis on management of infectious/inflammatory disorders.氟代脱氧葡萄糖正电子发射断层扫描(FDG-PET)成像对日常医学实践产生了无与伦比的影响,重点介绍其在感染性/炎症性疾病管理方面的最新情况。
Eur J Nucl Med Mol Imaging. 2020 Jan;47(1):18-27. doi: 10.1007/s00259-019-04490-6. Epub 2019 Sep 4.
8
Cerebral glucose metabolic prediction from amnestic mild cognitive impairment to Alzheimer's dementia: a meta-analysis.从遗忘型轻度认知障碍到阿尔茨海默病痴呆的脑葡萄糖代谢预测:一项荟萃分析。
Transl Neurodegener. 2018 Apr 23;7:9. doi: 10.1186/s40035-018-0114-z. eCollection 2018.